{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T16:14:08Z","timestamp":1791994448267,"version":"4.4.0"},"reference-count":30,"publisher":"American Psychiatric Association Publishing","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JNP"],"published-print":{"date-parts":[[2004,2]]},"DOI":"10.1176\/jnp.16.1.57","type":"journal-article","created":{"date-parts":[[2014,12,17]],"date-time":"2014-12-17T23:13:54Z","timestamp":1418858034000},"page":"57-62","source":"Crossref","is-referenced-by-count":22,"title":["A Comparison of Family History of Psychiatric Disorders Among Patients With Early- and Late-Onset Alzheimer\u2019s Disease"],"prefix":"10.1176","volume":"16","author":[{"given":"Gayatri","family":"Devi","sequence":"first","affiliation":[{"name":"Received December 12, 2001; revised July 9, 2002; accepted October 15, 2002. From the New York Memory and Healthy Aging Services (G. Devi), the Departments of Medicine (Neurology) (G. Devi) and Psychiatry (G. Devi) of Lenox Hill Hospital, G. H. Sergievsky Center (J Williamson, F Massoud, K Anderson, Y Stern, R Mayeux); the Department of Neurology (K Anderson, Y Stern, R Mayeux) and Psychiatry (K Anderson, DP Devanand) and the Taub Alzheimer\u2019s Disease Research Center (K Anderson, Y Stern, DP Devanand, R..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Williamson","sequence":"additional","affiliation":[{"name":"Received December 12, 2001; revised July 9, 2002; accepted October 15, 2002. From the New York Memory and Healthy Aging Services (G. Devi), the Departments of Medicine (Neurology) (G. Devi) and Psychiatry (G. Devi) of Lenox Hill Hospital, G. H. Sergievsky Center (J Williamson, F Massoud, K Anderson, Y Stern, R Mayeux); the Department of Neurology (K Anderson, Y Stern, R Mayeux) and Psychiatry (K Anderson, DP Devanand) and the Taub Alzheimer\u2019s Disease Research Center (K Anderson, Y Stern, DP Devanand, R..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fadi","family":"Massoud","sequence":"additional","affiliation":[{"name":"Received December 12, 2001; revised July 9, 2002; accepted October 15, 2002. From the New York Memory and Healthy Aging Services (G. Devi), the Departments of Medicine (Neurology) (G. Devi) and Psychiatry (G. Devi) of Lenox Hill Hospital, G. H. Sergievsky Center (J Williamson, F Massoud, K Anderson, Y Stern, R Mayeux); the Department of Neurology (K Anderson, Y Stern, R Mayeux) and Psychiatry (K Anderson, DP Devanand) and the Taub Alzheimer\u2019s Disease Research Center (K Anderson, Y Stern, DP Devanand, R..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen","family":"Anderson","sequence":"additional","affiliation":[{"name":"Received December 12, 2001; revised July 9, 2002; accepted October 15, 2002. From the New York Memory and Healthy Aging Services (G. Devi), the Departments of Medicine (Neurology) (G. Devi) and Psychiatry (G. Devi) of Lenox Hill Hospital, G. H. Sergievsky Center (J Williamson, F Massoud, K Anderson, Y Stern, R Mayeux); the Department of Neurology (K Anderson, Y Stern, R Mayeux) and Psychiatry (K Anderson, DP Devanand) and the Taub Alzheimer\u2019s Disease Research Center (K Anderson, Y Stern, DP Devanand, R..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaakov","family":"Stern","sequence":"additional","affiliation":[{"name":"Received December 12, 2001; revised July 9, 2002; accepted October 15, 2002. From the New York Memory and Healthy Aging Services (G. Devi), the Departments of Medicine (Neurology) (G. Devi) and Psychiatry (G. Devi) of Lenox Hill Hospital, G. H. Sergievsky Center (J Williamson, F Massoud, K Anderson, Y Stern, R Mayeux); the Department of Neurology (K Anderson, Y Stern, R Mayeux) and Psychiatry (K Anderson, DP Devanand) and the Taub Alzheimer\u2019s Disease Research Center (K Anderson, Y Stern, DP Devanand, R..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. P.","family":"Devanand","sequence":"additional","affiliation":[{"name":"Received December 12, 2001; revised July 9, 2002; accepted October 15, 2002. From the New York Memory and Healthy Aging Services (G. Devi), the Departments of Medicine (Neurology) (G. Devi) and Psychiatry (G. Devi) of Lenox Hill Hospital, G. H. Sergievsky Center (J Williamson, F Massoud, K Anderson, Y Stern, R Mayeux); the Department of Neurology (K Anderson, Y Stern, R Mayeux) and Psychiatry (K Anderson, DP Devanand) and the Taub Alzheimer\u2019s Disease Research Center (K Anderson, Y Stern, DP Devanand, R..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Mayeux","sequence":"additional","affiliation":[{"name":"Received December 12, 2001; revised July 9, 2002; accepted October 15, 2002. From the New York Memory and Healthy Aging Services (G. Devi), the Departments of Medicine (Neurology) (G. Devi) and Psychiatry (G. Devi) of Lenox Hill Hospital, G. H. Sergievsky Center (J Williamson, F Massoud, K Anderson, Y Stern, R Mayeux); the Department of Neurology (K Anderson, Y Stern, R Mayeux) and Psychiatry (K Anderson, DP Devanand) and the Taub Alzheimer\u2019s Disease Research Center (K Anderson, Y Stern, DP Devanand, R..."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"230","reference":[{"key":"R46881","doi-asserted-by":"crossref","unstructured":"Van Broeckhoven, CL: Molecular genetics of Alzheimer\u2019s Disease: identification of genes and gene mutations. Eur Neurol 1995; 35:8\u201319.","DOI":"10.1159\/000117083"},{"key":"R46882","doi-asserted-by":"crossref","unstructured":"Cruts M, Van Broeckhoven C: Molecular genetics of Alzheimer\u2019s Disease. Ann Med 1998; 30(6):560\u2013566","DOI":"10.3109\/07853899809002605"},{"key":"R46884","doi-asserted-by":"crossref","unstructured":"Mirra SS: Neuropathological assessment of Alzheimer\u2019s Disease: the experience of the Consortium to Establish a Registry for Alzheimer\u2019s Disease. International Psychogeriatrics. 9 Suppl 1:263\u20138; discussion 269\u2013272, 1997","DOI":"10.1017\/S1041610297004985"},{"key":"R46885","doi-asserted-by":"crossref","unstructured":"Campion D, Brice A, Hannequin D, et al: A large pedigree with early-onset Alzheimer\u2019s Disease: clinical, neuropathologic, and genetic characterization. Neurology 1995; 45(1):80\u201385","DOI":"10.1212\/WNL.45.1.80"},{"key":"R46886","unstructured":"Mayeux R, Saunders AM, Shea S, et al: Utility of the apolipoprotein E genotype in the diagnosis of Alzheimer\u2019s Disease. Alzheimer\u2019s Disease Centers Consortium on Apolipoprotein E and Alzheimer\u2019s Disease N Engl J Med 1998; 338(8):506\u2013511"},{"key":"R46887","doi-asserted-by":"crossref","unstructured":"Bird TD, Sumi SM, Nemens EJ, et al: Phenotypic heterogeneity in familial Alzheimer\u2019s Disease: a study of 24 kindreds.  Annals of Neurology 1989; 25(1):12\u201325","DOI":"10.1002\/ana.410250104"},{"key":"R46888","doi-asserted-by":"crossref","unstructured":"Mullan M. Bennett C. Figueredo C. et al: Clinical features of early onset, familial Alzheimer\u2019s Disease linked to chromosome 14. Am J Med Genet 1995; 60(1):44\u201352","DOI":"10.1002\/ajmg.1320600109"},{"key":"R46889","doi-asserted-by":"crossref","unstructured":"Mangone CA, Castano EM, Levy E, et al. Early onset Alzheimer\u2019s Disease in a South American pedigree from Argentina.  Acta Neurologica Scandinavica 1995; 91(1):6\u201313","DOI":"10.1111\/j.1600-0404.1995.tb05835.x"},{"key":"R468810","doi-asserted-by":"crossref","unstructured":"Rubin EH, Kinscherf DA, Morris JC: Psychopathology in younger versus older persons with very mild and mild dementia of the Alzheimer type. Am J Psychiatry 1993; 150:639\u2013642","DOI":"10.1176\/ajp.150.4.639"},{"key":"R468811","doi-asserted-by":"crossref","unstructured":"Pearlson GD, Ross CA, Lohr WD et al: Association between family history of affective disorder and depressive syndrome in Alzheimer\u2019s Disease. Am J Psychiatry 1990; 147(4):452\u2013456","DOI":"10.1176\/ajp.147.4.452"},{"key":"R468812","doi-asserted-by":"crossref","unstructured":"Strauss ME and Ogrocki PK: Confirmation of an association between family history of affective disorder and the depressive syndrome in Alzheimer\u2019s Disease. Am J Psychiatry 1996; 153:1340\u20131342","DOI":"10.1176\/ajp.153.10.1340"},{"key":"R468813","doi-asserted-by":"crossref","unstructured":"Luchins DJ, Cohen D, Hanrahan P et al: Are there clinical differences between familial and nonfamilial Alzheimer\u2019s Disease? Am J Psychiatry 1992; 149:1023\u20131027","DOI":"10.1176\/ajp.149.8.1023"},{"key":"R468814","doi-asserted-by":"crossref","unstructured":"Lyketsos CG, Tune LE, Pearlson G, et al: Major depression in Alzheimer\u2019s Disease. An interaction between gender and family history. Psychosomatics 1996; 37(4):380\u2013384","DOI":"10.1016\/S0033-3182(96)71552-9"},{"key":"R468815","doi-asserted-by":"crossref","unstructured":"Andreasen NC, Endicott J, Spitzer RL, et al: The family history method using diagnostic criteria: Reliability & validity. Arch Gen Psychiatry 1997; 34:1229\u20131235","DOI":"10.1001\/archpsyc.1977.01770220111013"},{"key":"R468816","doi-asserted-by":"crossref","unstructured":"Silverman JM, Raiford K, Edland S et al: The Consortium to Establish a Registry for Alzheimer\u2019s Disease (CERAD). Part VI. Family history assessment: A multicenter study of first-degree relatives of Alzheimer\u2019s Disease patients and nondemented spouse controls. Neurology 1994; 44:1253\u20131259","DOI":"10.1212\/WNL.44.7.1253"},{"key":"R468817","doi-asserted-by":"crossref","unstructured":"Devi G, Marder K, Schofield PW et al: Validity of family history for the diagnosis of dementia among siblings of patients with late onset Alzheimer\u2019s Disease. Genet Epidemiol 1998; 15:215\u2013223","DOI":"10.1002\/(SICI)1098-2272(1998)15:3<215::AID-GEPI1>3.0.CO;2-3"},{"key":"R468818","doi-asserted-by":"crossref","unstructured":"Jacobs DM, Sano M, Albert S, et al: Cross-cultural neuropsychological assessment: a comparison of randomly selected, demographically, matched cohorts of English- and Spanish-speaking older adults. J Clin Exp Neuropsychol 1997; 19:331\u2013339","DOI":"10.1080\/01688639708403862"},{"key":"R468819","doi-asserted-by":"crossref","unstructured":"McKhann G, Drachman D, Folstein M et al: Clinical diagnosis of Alzheimer\u2019s Disease: report of the NINCDS-ADRDA Work Group under the auspices of the Department of Health and Human Services Task Force on Alzheimer\u2019s Disease. Neurology 1984; 34:939\u2013944","DOI":"10.1212\/WNL.34.7.939"},{"key":"R468820","doi-asserted-by":"crossref","unstructured":"Hughes CP, Berg L, Danziger WL, et al: A new clinical scale for the staging of dementia. Br J Psychiatry 1982; 140:566\u2013572","DOI":"10.1192\/bjp.140.6.566"},{"key":"R468821","doi-asserted-by":"crossref","unstructured":"Morris JC, McKeel DW, Storandt M, et al: Very mild Alzheimer\u2019s Disease: informant based clinical, psychometric, and pathologic distinction from normal aging. Neurology 1991; 41:469\u2013478","DOI":"10.1212\/WNL.41.4.469"},{"key":"R468822","doi-asserted-by":"crossref","unstructured":"Martin RL, Gerteis J, Gabrielli WF: A family-genetic study of dementia of Alzheimer's type. Arch Gen Psychiatry 1988; 45:894\u2013900","DOI":"10.1001\/archpsyc.1988.01800340016002"},{"key":"R468823","doi-asserted-by":"crossref","unstructured":"Sweet RA, Nimgaonkar VL, Devlin B et al: Increased familial risk of the psychotic phenotype in Alzheimer disease. Neurology 2002; 58:907\u2013911","DOI":"10.1212\/WNL.58.6.907"},{"key":"R468825","doi-asserted-by":"crossref","unstructured":"Byerley W, Hoff M, Holik J et al: Linkage analysis between schizophrenia and index simple-sequence loci for chromosome 21. Hum Hered 1995; 45:49\u201352","DOI":"10.1159\/000154254"},{"key":"R468826","doi-asserted-by":"crossref","unstructured":"Fukuda R, Hattori M, Sasaki T et al: No evidence for a point mutation at codon 713 and 717 of amyloid precursor protein gene in Japanese schizophrenics. Japanese J Hum Gen 1993; 38:407\u201311","DOI":"10.1007\/BF01907987"},{"key":"R468829","doi-asserted-by":"crossref","unstructured":"Tsuang D, DiGiacomo L, Lipe H, et al: Familial aggregation of schizophrenia-like symptoms in Huntington's disease. Am J Med Genet 1998; 81(4):323\u2013327","DOI":"10.1002\/(SICI)1096-8628(19980710)81:4<323::AID-AJMG9>3.0.CO;2-U"},{"key":"R468830","doi-asserted-by":"crossref","unstructured":"Benton CS, de Silva R, Rutledge SL, et al: Molecular and clinical studies in SCA-7 define a broad clinical spectrum and the infantile phenotype. Neurology 1998; 51(4):1081\u20131086","DOI":"10.1212\/WNL.51.4.1081"},{"key":"R468831","doi-asserted-by":"crossref","unstructured":"Farrer LA, O'Sullivan DM, Cupples LA, et al: Assessment of genetic risk for Alzheimer\u2019s Disease among first-degree relatives. Ann Neurol 1989; 25:485\u2013493","DOI":"10.1002\/ana.410250511"},{"key":"R468832","doi-asserted-by":"crossref","unstructured":"Huff JF, Auerbach J, Chakravarti A, et al: Risk of dementia in relatives of patients with Alzheimer\u2019s Disease. Neurology 1988; 38:786\u2013790","DOI":"10.1212\/WNL.38.5.786"},{"key":"R468833","doi-asserted-by":"crossref","unstructured":"Breitner JCS, Silverman JM, Mohs RC, Davis KL. Familial aggregation in Alzheimer\u2019s Disease: Comparison of risk among relatives of early- and late-onset cases, and among male and female relatives in successive generations. Neurology 1988; 38:207\u2013212","DOI":"10.1212\/WNL.38.2.207"},{"key":"R468834","doi-asserted-by":"crossref","unstructured":"Massoud F, Devi G, Stern Y, et al: A clinicopathological comparison of community-based and clinic-based cohorts of patients with dementia. Arch Neurol 1999; 56:1368\u20131373","DOI":"10.1001\/archneur.56.11.1368"}],"container-title":["The Journal of Neuropsychiatry and Clinical Neurosciences"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/psychiatryonline.org\/doi\/10.1176\/jnp.16.1.57","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,30]],"date-time":"2024-07-30T23:52:39Z","timestamp":1722383559000},"score":1,"resource":{"primary":{"URL":"https:\/\/psychiatryonline.org\/doi\/10.1176\/jnp.16.1.57"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,2]]},"references-count":30,"aliases":["10.1176\/appi.neuropsych.16.1.57"],"journal-issue":{"issue":"1","published-print":{"date-parts":[[2004,2]]}},"alternative-id":["10.1176\/jnp.16.1.57"],"URL":"https:\/\/doi.org\/10.1176\/jnp.16.1.57","relation":{},"ISSN":["0895-0172","1545-7222"],"issn-type":[{"value":"0895-0172","type":"print"},{"value":"1545-7222","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,2]]}}}