{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T12:08:10Z","timestamp":1788782890475,"version":"build-2803163510"},"reference-count":4,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2021,7,27]],"date-time":"2021-07-27T00:00:00Z","timestamp":1627344000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The American Surgeon\u2122"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:p>We aimed to evaluate the efficacy and safety of endoanal ultrasound (EAUS)\u2013guided botulinum toxin (BT) in the treatment of chronic anal fissure (CAF). All patients were classified into 2 groups: conventional and EAUS groups. In total, 90 units of BT were injected into the internal anal sphincter at the 3, 6, and 9 o\u2019clock positions in the EAUS group. An injection was performed into the intersphincteric space at the 3, 6, and 9 o\u2019clock positions in the conventional group. Adverse effects and efficacy were analyzed. There were 44 patients: 26 in the conventional group and 18 in the EAUS group. Pain and incontinence rates were similar between groups ( P &gt; .05). The efficacy rate was higher in the EAUS group (69.23%) than in the conventional group (81.82%), but this difference was not significant ( P = .466). EAUS\u2013guided BT injection is safe and effective in patients with CAFs.<\/jats:p>","DOI":"10.1177\/00031348211034750","type":"journal-article","created":{"date-parts":[[2021,7,27]],"date-time":"2021-07-27T11:06:05Z","timestamp":1627383965000},"page":"2125-2128","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Efficacy and Safety of Endoanal Ultrasound\u2013Guided Botulinum Toxin in Chronic Anal Fissure"],"prefix":"10.1177","volume":"89","author":[{"given":"\u00c7agri","family":"Akalin","sequence":"first","affiliation":[{"name":"Department of General Surgery, Ordu Training and Research Hospital, Ordu, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayse Burcu","family":"Yavuzarslan","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Ordu Training and Research Hospital, Ordu, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cihangir","family":"Akyol","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Ankara University School of Medicine, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,7,27]]},"reference":[{"key":"bibr1-00031348211034750","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000000735"},{"key":"bibr2-00031348211034750","doi-asserted-by":"publisher","DOI":"10.1007\/DCR.0b013e3181e23dfe"},{"key":"bibr3-00031348211034750","doi-asserted-by":"publisher","DOI":"10.1016\/s0002-9610(99)00255-x"},{"key":"bibr4-00031348211034750","doi-asserted-by":"publisher","DOI":"10.4103\/njcp.njcp_14_20"}],"container-title":["The American Surgeon\u2122"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00031348211034750","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/00031348211034750","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00031348211034750","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T12:36:10Z","timestamp":1777379770000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/00031348211034750"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,27]]},"references-count":4,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,5]]}},"alternative-id":["10.1177\/00031348211034750"],"URL":"https:\/\/doi.org\/10.1177\/00031348211034750","relation":{},"ISSN":["0003-1348","1555-9823"],"issn-type":[{"value":"0003-1348","type":"print"},{"value":"1555-9823","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7,27]]}}}