{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T07:40:39Z","timestamp":1777448439434,"version":"3.51.4"},"reference-count":13,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The American Surgeon\u2122"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Bleeding complications are a risk associated with hemorrhoid procedures. Despite the prevalence of anticoagulant and antiplatelet therapies, including newer direct oral anticoagulants (DOACs) in the aging patient population there is a paucity of data regarding the impact of the use of antithrombotic therapy (AT) especially DOACs, on bleeding complications of hemorrhoid procedures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively reviewed charts of patients who had undergone a total of 1152 procedures, including hemorrhoid excision and ligation, at a single institution in the years 2016-2018. We noted whether they were prescribed AT, the indication for therapy, perioperative medication management, whether a PBE occurred, and how the PBE was managed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>PBE\u2019s were noted in 5.92% of patients on ATs, as opposed to 2.66% of patients not on ATs ( P = .014.) The odds ratio of having a PBE when on ATs vs not on ATs is 2.3 (95% CI 1.21 to 4.38, P = .011). Seven out of 40 (17.5%) total PBE\u2019s required hospital admission or repeat procedure, and this was not associated with AT use. Surprisingly, although males represented most of the patients on ATs, females were statistically more likely to have a PBE following a hemorrhoidectomy if on ATs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Patients on AT have an elevated risk of PBE compared to patients not on AT. No significant difference was found between the two groups when considering only those PBE\u2019s severe enough to require hospital admission or repeat procedure. Further research is required to establish clear guidelines regarding the perioperative management of AT for hemorrhoid procedures.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/00031348221124332","type":"journal-article","created":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T10:35:55Z","timestamp":1662028555000},"page":"4610-4615","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["The Impact of Antithrombotic Medications on Postoperative Bleeding Events Following Hemorrhoidectomy"],"prefix":"10.1177","volume":"89","author":[{"given":"Katherine R.","family":"Dean","sequence":"first","affiliation":[{"name":"Prisma Health, Colon and Rectal Surgery, Greenville, SC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haritha","family":"Pavuluri","sequence":"additional","affiliation":[{"name":"University of South Carolina School of Medicine-Greenville, Greenville, SC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"Fox","sequence":"additional","affiliation":[{"name":"New Hanover Regional Medical Center\/Colon and Rectal Surgery, Wilmington, NC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiyan","family":"Tan","sequence":"additional","affiliation":[{"name":"School of Mathematical and Statistical Sciences, Clemson University, Clemson, SC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin","family":"Watson","sequence":"additional","affiliation":[{"name":"Prisma Health, General Surgery, Greenville, SC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9783-0382","authenticated-orcid":false,"given":"Jacqueline Grace","family":"Wallenborn","sequence":"additional","affiliation":[{"name":"Prisma Health, General Surgery, Greenville, SC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George A.","family":"Blestel","sequence":"additional","affiliation":[{"name":"Prisma Health, Colon and Rectal Surgery, Greenville, SC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,9,1]]},"reference":[{"key":"bibr1-00031348221124332","doi-asserted-by":"publisher","DOI":"10.1016\/j.gcb.2010.10.001"},{"key":"bibr2-00031348221124332","first-page":"e14983","volume":"13","author":"Maemoto R","year":"2021","journal-title":"Cureus"},{"key":"bibr3-00031348221124332","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-021-03895-w"},{"key":"bibr4-00031348221124332","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-018-3176-6"},{"key":"bibr5-00031348221124332","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-004-6366-y"},{"key":"bibr6-00031348221124332","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)60243-4"},{"key":"bibr7-00031348221124332","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.120.017559"},{"key":"bibr8-00031348221124332","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0197583"},{"key":"bibr9-00031348221124332","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2015.05.044"},{"key":"bibr10-00031348221124332","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.121.022644"},{"key":"bibr11-00031348221124332","doi-asserted-by":"publisher","DOI":"10.1378\/chest.11-2292"},{"key":"bibr12-00031348221124332","doi-asserted-by":"publisher","DOI":"10.1378\/chest.11-2298"},{"key":"bibr13-00031348221124332","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2020002335"}],"container-title":["The American Surgeon\u2122"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00031348221124332","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/00031348221124332","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00031348221124332","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T12:37:56Z","timestamp":1777379876000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/00031348221124332"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,1]]},"references-count":13,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2023,11]]}},"alternative-id":["10.1177\/00031348221124332"],"URL":"https:\/\/doi.org\/10.1177\/00031348221124332","relation":{},"ISSN":["0003-1348","1555-9823"],"issn-type":[{"value":"0003-1348","type":"print"},{"value":"1555-9823","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,1]]}}}