{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T07:41:32Z","timestamp":1777448492892,"version":"3.51.4"},"reference-count":13,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2023,5,15]],"date-time":"2023-05-15T00:00:00Z","timestamp":1684108800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The American Surgeon\u2122"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:p>Anorectal manifestations of monkeypox are increasingly being recognized as a potentially serious complication. We present the case of an HIV-positive, tecovirimat-treated male presenting with monkeypox virus-associated severe proctitis with associated perianal pathology. Despite the use of antiviral agents and intravenous vaccinia immune globulin, the monkeypox-associated perianal lesions evolved into abscesses, requiring incision and drainage. This report highlights a multidisciplinary approach involving surgery for anorectal complications of monkeypox virus-associated proctitis and perianal lesions. Surgery may offer immediate relief and reduce the potential long-term morbidity associated with severe monkeypox virus-associated rectal and perianal manifestations refractory to available medical countermeasures.<\/jats:p>","DOI":"10.1177\/00031348231177931","type":"journal-article","created":{"date-parts":[[2023,5,15]],"date-time":"2023-05-15T15:54:21Z","timestamp":1684166061000},"page":"6370-6373","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Anorectal Manifestations of Treatment-Refractory Monkeypox Requiring Surgical Intervention"],"prefix":"10.1177","volume":"89","author":[{"given":"Patrick","family":"Cherfan","sequence":"first","affiliation":[{"name":"DeWitt Daughtry Family Department of Surgery, University of Miami Miller School of Medicine, Miami, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elie","family":"Massaad","sequence":"additional","affiliation":[{"name":"Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vanessa W.","family":"Hui","sequence":"additional","affiliation":[{"name":"DeWitt Daughtry Family Department of Surgery, University of Miami Miller School of Medicine, Miami, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,5,15]]},"reference":[{"issue":"5","key":"bibr1-00031348231177931","first-page":"593","volume":"46","author":"Ladnyj ID","year":"1972","journal-title":"Bull World Health Organ"},{"key":"bibr2-00031348231177931","unstructured":"CDC. 2022 outbreak cases and data. Centers for disease control and prevention. https:\/\/www.cdc.gov\/poxvirus\/monkeypox\/response\/2022\/index.html. Published December 8, 2022. Accessed December 10, 2022."},{"key":"bibr3-00031348231177931","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2207323"},{"key":"bibr4-00031348231177931","unstructured":"for Disease Control C, Prevention O. Clinical considerations for treatment and prophylaxis of Monkeypox virus infection in people with HIV. 2022. Published online."},{"key":"bibr5-00031348231177931","doi-asserted-by":"publisher","DOI":"10.7326\/L22-0300"},{"key":"bibr6-00031348231177931","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000002590"},{"key":"bibr7-00031348231177931","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(22)00228-6"},{"key":"bibr8-00031348231177931","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(22)01436-2"},{"key":"bibr9-00031348231177931","doi-asserted-by":"crossref","first-page":"e072410","DOI":"10.1136\/bmj-2022-072410","volume":"378","author":"Patel A","year":"2022","journal-title":"BMJ"},{"key":"bibr10-00031348231177931","unstructured":"CDC. Monkeypox in the U.S. Centers for disease control and prevention. https:\/\/www.cdc.gov\/poxvirus\/monkeypox\/if-sick\/treatment.html. Published December 8, 2022. Accessed December 11, 2022."},{"key":"bibr11-00031348231177931","doi-asserted-by":"publisher","DOI":"10.1097\/OLQ.0000000000001694"},{"key":"bibr12-00031348231177931","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciac737"},{"key":"bibr13-00031348231177931","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-022-01896-7"}],"container-title":["The American Surgeon\u2122"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00031348231177931","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/00031348231177931","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00031348231177931","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T12:38:04Z","timestamp":1777379884000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/00031348231177931"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,15]]},"references-count":13,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2023,12]]}},"alternative-id":["10.1177\/00031348231177931"],"URL":"https:\/\/doi.org\/10.1177\/00031348231177931","relation":{},"ISSN":["0003-1348","1555-9823"],"issn-type":[{"value":"0003-1348","type":"print"},{"value":"1555-9823","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,15]]}}}