{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T16:06:07Z","timestamp":1780934767570,"version":"3.54.1"},"reference-count":48,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2023,6,13]],"date-time":"2023-06-13T00:00:00Z","timestamp":1686614400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The American Surgeon\u2122"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Surgery is an effective clinical approach that has been used for the treatment of gastric lymphoma. However, its specific effect on the prognosis of patients with gastric lymphoma remains largely unknown. The current meta-analysis aimed to identify the effect of surgery on the prognosis of gastric lymphoma.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We searched the MEDLINE, Embase, and Cochrane Central databases to obtain relevant studies investigating the influence of surgery on overall survival (OS) and relapse-free survival (RFS). We extracted the hazard ratios (HRs) and associated 95% confidence intervals (CIs) of each included report for pooled analysis. We assessed heterogeneity (I\n                      <jats:sup>2<\/jats:sup>\n                      statistic) and funnel plots to select the data models and evaluate publication bias.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Ultimately, we included 12 studies containing 26 comparisons in the current quantitative meta-analysis. The analysis revealed that surgery had no significant effect on OS (HR .83, P = .13) or RFS (HR .78, P = .08). However, subgroup analysis revealed that the effect of surgery on OS differed significantly between the surgery plus conservative therapy subgroup and the conservative therapy alone groups, with HR = .69 ( P = .01). No significant publication bias was detected regarding the main outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Surgery had a limited effect on the prognosis of patients with gastric lymphoma. However, the use of surgery as an additional therapy may confer potential benefits. This was an interesting research direction, and additional high-quality, large-scale randomized controlled trials should be conducted.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/00031348231183126","type":"journal-article","created":{"date-parts":[[2023,6,13]],"date-time":"2023-06-13T04:15:42Z","timestamp":1686629742000},"page":"6147-6156","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["The Effect of Surgery on the Prognosis of Gastric Lymphoma: A Meta-analysis"],"prefix":"10.1177","volume":"89","author":[{"given":"Min","family":"Shi","sequence":"first","affiliation":[{"name":"Department of Pathophysiology, School of Basic Medical Sciences, Weifang Medical University, Weifang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"Yao","sequence":"additional","affiliation":[{"name":"School of Medicine, Huanggang Polytechnic College, Huanggang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haifeng","family":"Ding","sequence":"additional","affiliation":[{"name":"School of Medicine, Huanggang Polytechnic College, Huanggang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Yang","sequence":"additional","affiliation":[{"name":"School of Nursing, Huanggang Polytechnic College, Huanggang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cong","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Medicine, Huanggang Polytechnic College, Huanggang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Wu","sequence":"additional","affiliation":[{"name":"Liuzhou Key Laboratory of Infection Disease and Immunology, Guangxi Health Commission Key Laboratory of Clinical Biotechnology, Liuzhou People\u2019s Hospital Affiliated to Guangxi Medical University, Liuzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7340-3762","authenticated-orcid":false,"given":"Tao","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Pathophysiology, School of Basic Medical Sciences, Weifang Medical University, Weifang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,6,13]]},"reference":[{"key":"bibr1-00031348231183126","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v10.i1.5"},{"key":"bibr2-00031348231183126","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000004250"},{"key":"bibr3-00031348231183126","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v17.i6.697"},{"issue":"4","key":"bibr4-00031348231183126","doi-asserted-by":"crossref","first-page":"712","DOI":"10.4103\/0377-4929.91502","volume":"54","author":"Arora N","year":"2011","journal-title":"Indian J Pathol 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