{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T07:51:48Z","timestamp":1777449108829,"version":"3.51.4"},"reference-count":20,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2024,4,22]],"date-time":"2024-04-22T00:00:00Z","timestamp":1713744000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The American Surgeon\u2122"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The minimum weight for enterostomy closure (EC) in infants remains debated with the current acceptable cut-off of &gt;2\u00a0kg. As enterostomy-related complications or high enterostomy output (&gt;30cc\/kg\/d) may prohibit a premature infant from reaching 2\u00a0kg, additional data is needed to evaluate the safety of EC in infants &lt;2\u00a0kg. The objective of this study was to evaluate postoperative outcomes in low body weight (&lt;2\u00a0kg) infants undergoing EC compared to larger infants.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We performed a multi-center retrospective analysis from 1\/1\/2012-12\/31\/2022 of all infants (age &lt;1 year) who were &lt;4\u00a0kg at time of EC. Primary outcomes included postoperative complications and 30-day mortality. Non-parametric analysis was performed using the Kruskal-Wallis one-way analysis of variance and chi-square tests. Univariable logistic regression was performed to identify factors associated with postoperative complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 92 infants, 15 infants (16.3%) underwent EC at &lt;2\u00a0kg, 16 (17.4%) at 2-2.49\u00a0kg, 31 (33.7%) at 2.5-2.99\u00a0kg, and 30 (32.6%) at \u22653\u00a0kg. Infants &lt;2\u00a0kg at time of EC exhibited higher rates of hyperbilirubinemia ( P = .030), neurologic comorbidities ( P = .030), and high enterostomy output ( P = .041). There was no difference in postoperative complications ( P = .460) or 30-day mortality ( P = .460) between the &lt;2\u00a0kg group and larger weight groups. Low body weight was not associated with an increased risk for developing a postoperative complication (OR: 1.001, 95% CI: 1.001-1.001; P = .032).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our findings suggest that EC in infants &lt;2\u00a0kg may be safe with comparable postoperative outcomes to larger weight infants. Thus, the timing of EC should be based on the infant\u2019s physiologic status, in contrast to a predetermined minimum weight cut-off.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/00031348241248788","type":"journal-article","created":{"date-parts":[[2024,4,22]],"date-time":"2024-04-22T11:27:02Z","timestamp":1713785222000},"page":"2534-2542","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of Postoperative Outcomes After Enterostomy Closure in Low Body Weight Infants: A Multi-Center Retrospective Analysis"],"prefix":"10.1177","volume":"90","author":[{"given":"William G.","family":"Lee","sequence":"first","affiliation":[{"name":"Division of Pediatric Surgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA"},{"name":"Division of Pediatric Surgery, Children\u2019s Hospital Los Angeles, Los Angeles, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MaKayla L.","family":"O\u2019Guinn","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, Children\u2019s Hospital Los Angeles, Los Angeles, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olivia A.","family":"Keane","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, Children\u2019s Hospital Los Angeles, Los Angeles, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vikram","family":"Krishna","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shale J.","family":"Mack","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antoine","family":"Soliman","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Miller Children\u2019s and Women\u2019s Hospital, Long Beach, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dean M.","family":"Anselmo","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, Children\u2019s Hospital Los Angeles, Los Angeles, CA, USA"},{"name":"Division of Pediatric Surgery, Miller Children\u2019s and Women\u2019s Hospital, Long Beach, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nam X.","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, Children\u2019s Hospital Los Angeles, Los Angeles, CA, USA"},{"name":"Division of Pediatric Surgery, Miller Children\u2019s and Women\u2019s Hospital, Long Beach, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher P.","family":"Gayer","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, Children\u2019s Hospital Los Angeles, Los Angeles, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eugene S.","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eveline H.","family":"Shue","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA"},{"name":"Division of Pediatric Surgery, Miller Children\u2019s and Women\u2019s Hospital, Long Beach, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,4,22]]},"reference":[{"key":"bibr1-00031348241248788","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1005408"},{"key":"bibr2-00031348241248788","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2021-322040"},{"key":"bibr3-00031348241248788","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.133.8.875"},{"key":"bibr4-00031348241248788","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2009.06.005"},{"key":"bibr5-00031348241248788","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-019-03440-6"},{"key":"bibr6-00031348241248788","volume-title":"Presented at: 29th Annual Cool Topics in Neonatology Symposium","author":"Ronne 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