{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,15]],"date-time":"2026-08-15T06:19:58Z","timestamp":1786774798561,"version":"build-2736575974"},"reference-count":18,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2025,5,21]],"date-time":"2025-05-21T00:00:00Z","timestamp":1747785600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100006318","name":"Association for Academic Surgery Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006318","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Toyota, Subaru, and General Motors Corporations"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The American Surgeon\u2122"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The surgical management of peptic ulcer disease (PUD) has undergone profound changes over the past decades due to advances in medical management. Despite this reduced need for surgical intervention in the management of PUD, the absence of standardized, evidence-based guidelines for when gastroduodenal resection is warranted presents a significant gap in the literature. This review seeks to address this deficiency by summarizing the current literature and clarifying the indications for gastrectomy in the management of PUD, offering a framework for consistent and informed surgical decision-making.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We performed a literature review by searching PubMed, Google Scholar, and the Cochrane Library for studies of human participants, published in English between 2010 and 2024. Keywords utilized included \u201cgastrectomy,\u201d \u201csurgical management in PUD,\u201d \u201comental flap,\u201d and \u201cvagotomy.\u201d The results were summarized with contextual recommendations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>From the total of 6250 publications retrieved from the databases, we ultimately included 29 publications following a review of the abstracts and manuscripts. The management of peptic ulcer disease (PUD) has undergone a significant transformation, shifting from predominantly surgical interventions to advanced medical therapies, supported by innovations in pharmacotherapy, nutritional support, and endoscopic techniques.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Surgery, particularly gastrectomy, remains essential in specific cases such as large or multiple ulcers, ulcers associated with malignancy, and complicated cases that do not respond to other treatments. Emerging technologies continue to refine risk prediction and patient management, offering hope for further reducing surgical interventions. Despite these advancements, timely surgical intervention remains critical for managing life-threatening complications.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/00031348251341965","type":"journal-article","created":{"date-parts":[[2025,5,21]],"date-time":"2025-05-21T05:03:18Z","timestamp":1747803798000},"page":"1388-1391","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Cut to the Point: Revisiting the Role of Gastrectomy in Peptic Ulcer Disease"],"prefix":"10.1177","volume":"91","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-3613-1685","authenticated-orcid":false,"given":"Sarah D.","family":"Diaz","sequence":"first","affiliation":[{"name":"Division of Acute Care Surgery, Department of Surgery, University of Michigan, Ann Arbor, MI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5421-0386","authenticated-orcid":false,"given":"Raymond A.","family":"Jean","sequence":"additional","affiliation":[{"name":"Division of Acute Care Surgery, Department of Surgery, University of Michigan, Ann Arbor, MI, USA"},{"name":"Center for Healthcare Outcomes and Policy, University of Michigan, Ann Arbor, MI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Staci T.","family":"Aubry","sequence":"additional","affiliation":[{"name":"Division of Acute Care Surgery, Department of Surgery, University of Michigan, Ann Arbor, MI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,5,21]]},"reference":[{"issue":"1","key":"e_1_3_3_2_2","first-page":"e12","article-title":"The surgical management of complicated peptic ulcer disease: an EAST video presentation","volume":"93","author":"Hudnall A","year":"2022","unstructured":"Hudnall A, Bardes J. M, Coleman K, et al. The surgical management of complicated peptic ulcer disease: an EAST video presentation. J Trauma Acute Care Surg. 2022;93(1):e12-e16.","journal-title":"J Trauma Acute Care Surg"},{"key":"e_1_3_3_3_2","volume-title":"Risk Factors for Mortality in Emergently Admitted Patients with Acute Gastric Ulcer: An Analysis of 15,538 Patients in National Inpatient Sample, 2005-2014. International journal of environmental research and public health","author":"Idris M","year":"2022","unstructured":"Idris M, Smiley A, Patel S, Latifi R. Risk Factors for Mortality in Emergently Admitted Patients with Acute Gastric Ulcer: An Analysis of 15,538 Patients in National Inpatient Sample, 2005-2014. International journal of environmental research and public health. Switzerland: MDPI AG; 2022."},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-021-01769-0"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD011523.pub2"},{"key":"e_1_3_3_6_2","volume-title":"Pathogens","author":"Chan KS","year":"2024","unstructured":"Chan KS, Tan LYC, Balasubramaniam S, Shelat VG. Should empiric anti-fungals Be administered routinely for All patients with perforated peptic ulcers? A critical review of the existing literature. In: Pathogens. Basel: MDPI AG; 2024."},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.3390\/medicina57121345"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/den.14356"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12262-020-02358-w"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13017-019-0283-9"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm13041063"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.3389\/fsurg.2022.894775"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-015-3050-6"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.54646"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-020-06573-z"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1097\/TA.0000000000003357"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2020.07.039"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00068-019-01237-8"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1177\/03000605231206319"}],"container-title":["The American Surgeon\u2122"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00031348251341965","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/00031348251341965","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00031348251341965","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T12:37:50Z","timestamp":1777379870000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/00031348251341965"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,21]]},"references-count":18,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2025,8]]}},"alternative-id":["10.1177\/00031348251341965"],"URL":"https:\/\/doi.org\/10.1177\/00031348251341965","relation":{},"ISSN":["0003-1348","1555-9823"],"issn-type":[{"value":"0003-1348","type":"print"},{"value":"1555-9823","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,21]]}}}