{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T21:06:41Z","timestamp":1777756001843,"version":"3.51.4"},"reference-count":20,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T00:00:00Z","timestamp":1764201600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The American Surgeon\u2122"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Early identification of low-risk patients after curative gastric or colorectal surgery can enable safe, timely discharge. We evaluated two routinely available postoperative markers\u2014serum prealbumin (PA) and lymphocyte percentage (L%)\u2014as a simple rule-out strategy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This is a single-center retrospective cohort study with a temporal external validation set. Prealbumin (mg\/dL) and L% (%) were measured on postoperative day (POD)1\/3\/5. We prespecified a high-sensitivity threshold (sensitivity \u226590%) in the training cohort and assessed its performance in the validation cohort. Multivariable logistic models were fitted at POD3 and POD5.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Postoperative day 1 L% showed limited discrimination; analyses focused on POD3\/5. At both time points, PA and L% were independent protective predictors, with no effect modification by tumor site. Slim (PA + L%) and Full models had similar discrimination; both were well calibrated, and decision-curve analysis indicated clear net benefit over default strategies. Under the fixed high-sensitivity approach, the POD3 Slim model maintained high sensitivity and NPV with moderate specificity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>By POD3, combining PA and L% provides a low-cost, readily deployable, rule-out-oriented approach that supports safe early discharge within structured postoperative pathways. Multicenter prospective validation and impact studies are warranted.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/00031348251405539","type":"journal-article","created":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T19:55:33Z","timestamp":1764273333000},"page":"1730-1739","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Simple Postoperative Markers for Early Identification of Low-Risk Patients After Gastric or Colorectal Cancer Surgery: A Retrospective Cohort Study"],"prefix":"10.1177","volume":"92","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-2865-345X","authenticated-orcid":false,"given":"Duchen","family":"Li","sequence":"first","affiliation":[{"name":"Shandong First Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuezheng","family":"Jiang","sequence":"additional","affiliation":[{"name":"Shandong First Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xianpu","family":"Zhu","sequence":"additional","affiliation":[{"name":"Shandong First Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-7583-8811","authenticated-orcid":false,"given":"Hongyuan","family":"Chen","sequence":"additional","affiliation":[{"name":"Shandong Provincial Hospital Affiliated to Shandong First Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7060-6030","authenticated-orcid":false,"given":"Xiaoqiao","family":"Zhang","sequence":"additional","affiliation":[{"name":"Shandong Provincial Hospital Affiliated to Shandong First Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,11,27]]},"reference":[{"key":"e_1_3_7_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2022.101404"},{"key":"e_1_3_7_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000004341"},{"key":"e_1_3_7_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000003331"},{"key":"e_1_3_7_5_2","doi-asserted-by":"publisher","DOI":"10.1515\/CCLM.2002.222"},{"key":"e_1_3_7_6_2","doi-asserted-by":"publisher","DOI":"10.1177\/0004563220931885"},{"key":"e_1_3_7_7_2","doi-asserted-by":"publisher","DOI":"10.1080\/1354750X.2024.2402419"},{"key":"e_1_3_7_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-011-1719-z"},{"key":"e_1_3_7_9_2","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-016-5548-x"},{"key":"e_1_3_7_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00423-023-03186-8"},{"key":"e_1_3_7_11_2","doi-asserted-by":"publisher","DOI":"10.5604\/01.3001.0015.8385"},{"key":"e_1_3_7_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-025-03134-2"},{"key":"e_1_3_7_13_2","doi-asserted-by":"publisher","DOI":"10.1093\/jjco\/hyaa099"},{"key":"e_1_3_7_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/ncp.10588"},{"issue":"1","key":"e_1_3_7_15_2","first-page":"49","article-title":"The significance of changes in blood lymphocyte populations following surgical operations","volume":"56","author":"Hamid J","year":"1984","unstructured":"Hamid J, Bancewicz J, Brown R, Ward C, Irving MH, Ford WL. The significance of changes in blood lymphocyte populations following surgical operations. Clin Exp Immunol. 1984;56(1):49-57.","journal-title":"Clin Exp Immunol"},{"key":"e_1_3_7_16_2","doi-asserted-by":"publisher","DOI":"10.1536\/jhj.41.385"},{"key":"e_1_3_7_17_2","doi-asserted-by":"publisher","DOI":"10.2119\/molmed.2010.00178"},{"key":"e_1_3_7_18_2","doi-asserted-by":"publisher","DOI":"10.5114\/ceji.2014.47741"},{"key":"e_1_3_7_19_2","doi-asserted-by":"publisher","DOI":"10.3390\/biology14010076"},{"key":"e_1_3_7_20_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2024.1441020"},{"key":"e_1_3_7_21_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-024-05099-4"}],"container-title":["The American Surgeon\u2122"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00031348251405539","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/00031348251405539","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00031348251405539","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T12:19:20Z","timestamp":1777465160000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/00031348251405539"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,27]]},"references-count":20,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["10.1177\/00031348251405539"],"URL":"https:\/\/doi.org\/10.1177\/00031348251405539","relation":{},"ISSN":["0003-1348","1555-9823"],"issn-type":[{"value":"0003-1348","type":"print"},{"value":"1555-9823","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,27]]}}}