{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T18:04:13Z","timestamp":1785261853452,"version":"3.55.0"},"reference-count":29,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T00:00:00Z","timestamp":1768953600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The American Surgeon\u2122"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Follicular thyroid carcinoma (FTC) behaves differently from papillary thyroid carcinoma. Although early-stage FTC generally has favorable outcomes, risk within AJCC stage I-II is not uniform, and robust evidence focusing exclusively on this group is limited.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We identified 4220 patients with AJCC stage I-II FTC in the SEER database (2010-2022). The primary endpoint was disease-specific survival (DSS). We estimated cumulative incidence functions (CIFs) for thyroid cancer\u2013specific and other-cause mortality and evaluated prognostic factors using Fine-Gray competing-risk regression. Multivariable modeling and nomogram construction were not pursued because only one variable met significance in univariable analyses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Across follow-up, other-cause mortality exceeded thyroid cancer\u2013specific mortality; at \u223c10 years, other-cause death was \u223c6% while thyroid cancer\u2013specific death remained &lt;1.5%. In competing-risk regression, AJCC stage II was the sole significant predictor of thyroid cancer\u2013specific mortality vs stage I (SHR 7.76; 95% CI 2.09-28.8;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.002). Other demographic, tumor, and treatment variables were not significant or were non-estimable due to sparsity.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Early-stage FTC shows low cancer-specific mortality overall, but risk is concentrated in stage II, underscoring clinically meaningful heterogeneity within \u201cearly stage.\u201d These findings support stage-attuned counseling and follow-up and highlight the importance of competing-risk methods when interpreting outcomes in FTC.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/00031348261419769","type":"journal-article","created":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T06:57:42Z","timestamp":1769065062000},"page":"1975-1981","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Prognostic Factors and Competing Risk Analysis in Early-Stage Follicular Thyroid Carcinoma: A Population-Based Study"],"prefix":"10.1177","volume":"92","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1813-9687","authenticated-orcid":false,"given":"Isa","family":"Karaca","sequence":"first","affiliation":[{"name":"Suleyman Demirel University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1483-8176","authenticated-orcid":false,"given":"Ahmet Necati","family":"Sanli","sequence":"additional","affiliation":[{"name":"Abdulkadir Yuksel State Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1665-3607","authenticated-orcid":false,"given":"Bilal","family":"Turan","sequence":"additional","affiliation":[{"name":"Suleyman Demirel University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serdar","family":"Acar","sequence":"additional","affiliation":[{"name":"Suleyman Demirel University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deniz Esin","family":"Tekcan Sanli","sequence":"additional","affiliation":[{"name":"Gaziantep University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,1,21]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22041950"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-021-08450-3"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.3390\/molecules30091899"},{"key":"e_1_3_5_5_2","first-page":"e31294","article-title":"Synchronous sternal metastasectomy and total thyroidectomy for differentiated thyroid cancer: a rare case report","volume":"14","author":"Paspala A","year":"2022","unstructured":"Paspala A, Papakonstantinou D, Pikoulis E, Tomos PI, Nastos C. Synchronous sternal metastasectomy and total thyroidectomy for differentiated thyroid cancer: a rare case report. Cureus. 2022;14:e31294.","journal-title":"Cureus"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccr3.1177"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccr3.8959"},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.7150\/jca.101395"},{"key":"e_1_3_5_9_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41379-021-00907-6"},{"key":"e_1_3_5_10_2","doi-asserted-by":"publisher","DOI":"10.1177\/10507256251363120"},{"key":"e_1_3_5_11_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms26115173"},{"key":"e_1_3_5_12_2","first-page":"1217","article-title":"Multi-omics and management of follicular carcinoma of the thyroid","volume":"11","author":"Luvhengo TE","year":"2023","unstructured":"Luvhengo TE, Bombil I, Mokhtari A, et al. Multi-omics and management of follicular carcinoma of the thyroid. Multi-omics and management of follicular carcinoma of the thyroid. Biomedicines. 2023;11:1217.","journal-title":"Multi-omics and management of follicular carcinoma of the thyroid. Biomedicines"},{"key":"e_1_3_5_13_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2016.68.9372"},{"key":"e_1_3_5_14_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12902-023-01521-0"},{"key":"e_1_3_5_15_2","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2011.0535"},{"key":"e_1_3_5_16_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12880-024-01244-1"},{"key":"e_1_3_5_17_2","doi-asserted-by":"publisher","DOI":"10.15587\/2519-4798.2019.174444"},{"key":"e_1_3_5_18_2","doi-asserted-by":"publisher","DOI":"10.21037\/gs-20-273"},{"key":"e_1_3_5_19_2","doi-asserted-by":"publisher","DOI":"10.1507\/endocrj.EJ20-0025"},{"key":"e_1_3_5_20_2","doi-asserted-by":"publisher","DOI":"10.1507\/endocrj.EJ22-0077"},{"key":"e_1_3_5_21_2","doi-asserted-by":"crossref","unstructured":"Xu B Ronald AG. Critical Prognostic Parameters in the Anatomic Pathology Reporting of Differentiated Follicular Cell-Derived Thyroid Carcinoma. 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