{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T03:56:14Z","timestamp":1790654174620,"version":"4.1.0"},"reference-count":18,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T00:00:00Z","timestamp":1790294400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The American Surgeon\u2122"],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>While contrast-associated acute kidney injury (CA-AKI) is a recognized entity, data regarding CA-AKI risk after repeated intravascular (IV) contrast exposures in older adults remain limited. We hypothesized that repeated IV contrast exposures were not associated with AKI in geriatric trauma patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively studied patients aged \u226565 years at a level 1 trauma center from January to December 2023. Patients who underwent at least one computed tomography scan or arteriogram within 48 hours were included. Exclusion criteria were death within 48 hours or pre-admission renal replacement therapy. CA-AKI was defined using Kidney Disease: Improving Global Outcomes criteria. Adjusted risks of AKI and CA-AKI were estimated using logistic regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 1486 patients, 455 (30.6%), 881 (59.2%), and 150 (10.1%) received none, one and \u22652 contrast exposures respectively. AKI occurred in 126 (8.5%). CA-AKI occurred in 64 (6.2%) of 1031 patients who received IV contrast. Multivariate analyses showed that AKI was associated with receiving \u22652 exposures (odds ratio [95% confidence interval] 2.58 (1.42-4.59), but not with only one exposure (0.78 [0.50-1.24]). In patients who received contrast, \u22652 contrast exposures was an independent risk factor for CA-AKI (3.43 [1.89-6.09]). Admission estimated glomerular filtration rate, Charlson comorbidity index and diabetes mellitus were also independent risk factors for AKI and CA-AKI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>In geriatric trauma patients, receiving \u22652 contrast exposures was associated with AKI. Concomitant reduced renal function, diabetes mellitus and high comorbidity burden could identify a subgroup in whom greater attention to imaging strategy and contrast stewardship may be warranted.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/00031348261489293","type":"journal-article","created":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T16:54:03Z","timestamp":1790355243000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Acute Kidney Injury After Repeated Contrast Studies: Identifying a High-Risk Geriatric Trauma Population"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4799-2345","authenticated-orcid":false,"given":"Liron M.","family":"Fedida","sequence":"first","affiliation":[{"name":"Department of Surgery, Drexel University College of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-3882-3115","authenticated-orcid":false,"given":"Joshua N.","family":"Mikos","sequence":"additional","affiliation":[{"name":"Department of Surgery, Drexel University College of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-0567-1602","authenticated-orcid":false,"given":"William C.","family":"Van","sequence":"additional","affiliation":[{"name":"Department of Surgery, Drexel University College of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judah","family":"Womack","sequence":"additional","affiliation":[{"name":"Department of Surgery, Drexel University College of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyle","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Surgery, Drexel University College of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alison","family":"Muller","sequence":"additional","affiliation":[{"name":"Reading Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Butts","sequence":"additional","affiliation":[{"name":"Department of Surgery, Drexel University College of Medicine"},{"name":"Reading Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugene","family":"Reilly","sequence":"additional","affiliation":[{"name":"Department of Surgery, Drexel University College of Medicine"},{"name":"Reading Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5919-4095","authenticated-orcid":false,"given":"Adrian","family":"Ong","sequence":"additional","affiliation":[{"name":"Department of Surgery, Drexel University College of Medicine"},{"name":"Reading Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,9,25]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/TA.0000000000003735"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0211001"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.13122276"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1177\/08465371221083970"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2019192094"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.2147\/CIA.S55157"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.02.070"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2015121308"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cger.2009.04.001"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.3109\/0886022X.2010.495441"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.2290\/jcm12062166"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocpiqo.2020.08.012"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.3348\/kjr.2020.1153"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00068-024-02698-2"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1038\/kisup.2012.1"},{"key":"e_1_3_3_17_2","first-page":"164","article-title":"Risk scoring system for prediction of contrast-induced nephropathy in patients with pre-existing renal impairment undergoing percutaneous coronary intervention","volume":"53","author":"Chong E","year":"2012","unstructured":"Chong E, Shen L, Poh KK, Tan HC. 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