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The 2025 American Thyroid Association guideline and the International Neural Monitoring Study Group guidelines both recommend deferring contralateral resection when first-side RLN injury or persistent loss of signal is recognized, and prospective monitoring series show that terminating bilateral surgery in this setting reduces bilateral vocal cord paralysis without compromising patient satisfaction. What existing recommendations do not supply is an operative pathway: what should trigger the pause, how loss of signal should be troubleshot, what recovery threshold permits same-session completion, when laryngoscopy should occur, and how completion thyroidectomy should be reconsidered. This review synthesizes contemporary guideline language, prospective monitoring data, and published thyroidectomy malpractice decisions retrieved from Westlaw into a practical two-track intraoperative framework. Track A addresses visualized transection or a clearly nonviable nerve; Track B addresses persistent loss of signal without visualized injury, where amplitude recovery to at least half of baseline, confirmed by vagal stimulation, supports same-session completion. Published case law is used illustratively rather than epidemiologically and shows that adjudicated operative criticism has clustered around extent of resection and the decision to complete the second side rather than around the occurrence of nerve injury, while defense outcomes more often reflected accepted-risk anatomy, specific consent documentation, and adequate expert proof. Evidence favoring selective immediate completion is presented alongside the case for staging. The framework operationalizes rather than replaces existing guidance and supplies concrete troubleshooting, consent, and operative-note elements.<\/jats:p>","DOI":"10.1177\/00031348261496605","type":"journal-article","created":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T05:02:54Z","timestamp":1791867774000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Staged Thyroidectomy After First-Side Recurrent Laryngeal Nerve Injury or Loss of Signal: An Evidence-Based Operative Framework"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-4869-3402","authenticated-orcid":false,"given":"Tucker","family":"Bettis","sequence":"first","affiliation":[{"name":"Emory University School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Logan D.","family":"Glosser","sequence":"additional","affiliation":[{"name":"Emory University School of 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