{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T18:11:24Z","timestamp":1777399884435,"version":"3.51.4"},"reference-count":7,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2000,5,1]],"date-time":"2000-05-01T00:00:00Z","timestamp":957139200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Angiology"],"published-print":{"date-parts":[[2000,5]]},"abstract":"<jats:p>The monoclonal immunoglobulin products of plasma cell neoplasm can give rise to a variety of manifestations including hyperviscosity, amyloidosis, cryoglobulinemia, neuropathy, and renal failure. A 50-year-old woman with monoclonal cryoglobulinemia developed extensive gangrene and ulceration of both hands and feet over several weeks requiring bilateral below-elbow and below-knee amputations. This case illustrates the importance of qualitative properties of paraprotein.<\/jats:p>","DOI":"10.1177\/000331970005100511","type":"journal-article","created":{"date-parts":[[2008,7,28]],"date-time":"2008-07-28T17:57:07Z","timestamp":1217267827000},"page":"431-434","source":"Crossref","is-referenced-by-count":12,"title":["Monoclonal Cryoglobulinemia with Extensive Gangrene of All Four Extremities"],"prefix":"10.1177","volume":"51","author":[{"given":"Jasotha","family":"Sanmugarajah","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joel M.","family":"Schwartz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandor","family":"Friedman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shafkat","family":"Hussain","sequence":"additional","affiliation":[{"name":"Coney Island Hospital 2601 Ocean Parkway, Room 9N8 Brooklyn, NY 11235"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2000,5,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM195911052611906"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1982.03330200094018"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(74)90852-3"},{"key":"atypb4","first-page":"1061","volume":"29","author":"Raina V.","year":"1981","journal-title":"J Assoc Physicians India"},{"key":"atypb5","first-page":"785","volume":"35","author":"Bhaskar Kvs","year":"1987","journal-title":"J Assoc Physicians India"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-197011000-00021"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1159\/000250485"}],"container-title":["Angiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000331970005100511","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000331970005100511","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T10:16:01Z","timestamp":1777371361000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/000331970005100511"}},"subtitle":["A Case Report"],"short-title":[],"issued":{"date-parts":[[2000,5]]},"references-count":7,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2000,5]]}},"alternative-id":["10.1177\/000331970005100511"],"URL":"https:\/\/doi.org\/10.1177\/000331970005100511","relation":{},"ISSN":["0003-3197","1940-1574"],"issn-type":[{"value":"0003-3197","type":"print"},{"value":"1940-1574","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,5]]}}}