{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T18:11:53Z","timestamp":1777399913520,"version":"3.51.4"},"reference-count":25,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2000,8,1]],"date-time":"2000-08-01T00:00:00Z","timestamp":965088000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Angiology"],"published-print":{"date-parts":[[2000,8]]},"abstract":"<jats:p>The authors evaluated the long-term safety of expanded polytetrafluoroethylene (ePTFE) implants used in external valvuloplasty for treatment of incompetence of the long saphenous and common and superficial femoral veins. During a 15-year period patients with superficial and\/or deep venous disease and hypertension due to pure superficial or deep vein incompetence underwent an external valvuloplasty with ePTFE sutures, or an ePTFE cardiovascular patch placed as a sleeve around the incompetent vein segment, or an ePTFE tubular graft placed around the venous segment. Postoperative follow-up evaluations consisted of clinical examinations, high-resolution ultrasonography, and color duplex scanning, and a complete blood count performed at 1, 3 and 6 months, and repeated for at least 4 years, every 2 years after the procedure. A total of 101 patients (38 men and 63 women; mean [\u00b1 sd] age, 44 \u00b112 years) underwent external valvuloplasty between January 1983 and December 1998; 82 of them completed the 4-year follow-up. Forty of the 82 patients had been operated on for superficial vein incompetence, 42 for deep vein incompetence. Overall, the mean follow- up time was 7.8 \u00b1 3.6 years (range, 4 to 13). There were no infections, thromboses, foreign-body reactions to the ePTFE implants, or other prosthesis-related complications requiring explantation. One granuloma (noninfected) developed in association with a tubular ePTFE implant around a long saphenous vein, but it did not necessitate implant removal. Seven patients required (at least after 4 years) a second procedure for recurrent or new venous incompetence. Therefore, in this observational study, ePTFE implants used to treat or correct venous incompetence were well tolerated on a long- term basis.<\/jats:p>","DOI":"10.1177\/000331970005100804","type":"journal-article","created":{"date-parts":[[2008,7,28]],"date-time":"2008-07-28T17:57:07Z","timestamp":1217267827000},"page":"S27-S32","source":"Crossref","is-referenced-by-count":6,"title":["Expanded Polytetrafluoroethylene in External Valvuloplasty for Superficial or Deep Vein Incompetence"],"prefix":"10.1177","volume":"51","author":[{"given":"A.N.","family":"Nicolaides","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.M.","family":"Errichi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Incandela","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.T.","family":"De Sanctis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Laurora","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Ricci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Belcaro","sequence":"additional","affiliation":[{"name":"Via Vespucci 65 65100 Pescara Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2000,8,1]]},"reference":[{"key":"atypb1","first-page":"41","volume":"24","author":"Kistner RL","year":"1968","journal-title":"Straub Clin Proc"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1016\/0741-5214(88)90149-8"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1016\/0741-5214(88)90319-9"},{"key":"atypb4","first-page":"15","volume":"55","author":"Kistner RL","year":"1990","journal-title":"Straub Found Proc"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1016\/0741-5214(91)90188-Z"},{"key":"atypb6","first-page":"305","volume":"89","author":"Belcaro G.","year":"1989","journal-title":"Acta Chir Belg"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1177\/026835559200700310"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1177\/153857449302700208"},{"key":"atypb9","first-page":"395","volume":"34","author":"Belcaro G.","year":"1993","journal-title":"J Cardiovasc Surg"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1177\/026835559400900403"},{"key":"atypb11","unstructured":"Lane RJ: Repair of venous valves using silicone cuffs. 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