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Thrombin generation during the unstable period was significantly greater than that at rest in the healthy control group (p &lt; 0.0001) and that during the stable period (p &lt; 0.0001). Changes in thrombin gener ation were related to the time after onset of unstable angina, not to degree of improvement in the severity of coronary stenosis.<\/jats:p>","DOI":"10.1177\/000331970105201202","type":"journal-article","created":{"date-parts":[[2008,7,28]],"date-time":"2008-07-28T17:57:07Z","timestamp":1217267827000},"page":"811-818","source":"Crossref","is-referenced-by-count":2,"title":["Platelet-Dependent Thrombin Generation in Patients with Unstable Angina Pectoris"],"prefix":"10.1177","volume":"52","author":[{"given":"Yukihisa","family":"Hasumura","sequence":"first","affiliation":[{"name":"Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuo","family":"Aoki","sequence":"additional","affiliation":[{"name":"Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koichi","family":"Kawano","sequence":"additional","affiliation":[{"name":"Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masashi","family":"Homori","sequence":"additional","affiliation":[{"name":"Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Maki","sequence":"additional","affiliation":[{"name":"Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiko","family":"Hioki","sequence":"additional","affiliation":[{"name":"Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyozo","family":"Ishikawa","sequence":"additional","affiliation":[{"name":"Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideaki","family":"Yoshino","sequence":"additional","affiliation":[{"name":"Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2001,12,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.53.4.363"},{"key":"atypb2","first-page":"II-47","volume":"82","author":"Fuster V.","year":"1990","journal-title":"Circulation"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199201233260406"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199201303260506"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.85.5.1706"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(97)00129-0"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(95)00518-8"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(97)00005-3"},{"key":"atypb9","volume-title":"Unstable angina: diagnosis and management","author":"Braunwald E.","year":"1994"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.80.2.410"},{"key":"atypb11","volume-title":"Second report on diabetes mellitus","year":"1980"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1997.00440420033005"},{"key":"atypb13","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.75.1.156"},{"key":"atypb14","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.90.1.61"},{"key":"atypb15","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V54.3.659.659"},{"key":"atypb16","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V65.2.319.319"},{"key":"atypb17","first-page":"1","volume":"1180","author":"Zwaal Rfa","year":"1992","journal-title":"Biochem Biophys Acta"},{"key":"atypb18","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199303113281002"},{"key":"atypb19","doi-asserted-by":"publisher","DOI":"10.1016\/0049-3848(88)90060-6"},{"key":"atypb20","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.83.5.1685"},{"key":"atypb21","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.91.10.2520"}],"container-title":["Angiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000331970105201202","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000331970105201202","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T10:16:20Z","timestamp":1777371380000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/000331970105201202"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,12]]},"references-count":21,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2001,12]]}},"alternative-id":["10.1177\/000331970105201202"],"URL":"https:\/\/doi.org\/10.1177\/000331970105201202","relation":{},"ISSN":["0003-3197","1940-1574"],"issn-type":[{"value":"0003-3197","type":"print"},{"value":"1940-1574","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,12]]}}}