{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T18:14:42Z","timestamp":1777400082805,"version":"3.51.4"},"reference-count":41,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2002,1,1]],"date-time":"2002-01-01T00:00:00Z","timestamp":1009843200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Angiology"],"published-print":{"date-parts":[[2002,1]]},"abstract":"<jats:p>The disease characteristics, management, and outcome of Stenotrophomonas maltophilia endocarditis were evaluated by examining the reports on the subject identified through a comprehensive literature search. Twenty-three (17 male) cases of S. maltophilia endocarditis were identified. Mean age was 41 \u00b1 15 years. All patients presented with fever. Prosthetic valves were involved in 12 (52%) cases. Among native valves, the aortic valve was most frequently involved (50%), followed by the tricuspid valve (36%). Twenty (87%) patients had underlying risk factors for the development of endocarditis, including prior valvular or congen ital heart disease surgery (60%), intravenous drug abuse (32%), and infected intravascular lines (18%). The endocarditis was postoperative in 14 patients. Seventeen (74%) patients experienced complications including septic embolism (23%), cardiac abscesses (23%), and congestive heart failure ( 18%). A combination of two or more antibiotics was used in all cases except one. The frequently used antibiotics were aminoglycosides (59%), trimethoprim sulfamethoxazole (48%), and penicillins (48%). One half of the patients required cardiac surgery, but the proportion of surgically treated cases was higher among prosthetic valve endocarditis (62%). Mortality was 39% and was equally distributed between patients with prosthetic and native valve endocarditis. The S. maltophilia endocarditis carries high compli cation and mortality rates. The antibiotic regimen should consist of a combination of multiple antibiotics guided by the sensitivity panel. Early surgery may be considered in patients not responding to antibiotic treatment and in those with prosthetic valve endocarditis.<\/jats:p>","DOI":"10.1177\/000331970205300107","type":"journal-article","created":{"date-parts":[[2008,7,28]],"date-time":"2008-07-28T17:57:07Z","timestamp":1217267827000},"page":"49-55","source":"Crossref","is-referenced-by-count":39,"title":["Stenotrophomonas maltophilia Endocarditis: A Systematic Review"],"prefix":"10.1177","volume":"53","author":[{"given":"Ijaz A.","family":"Khan","sequence":"first","affiliation":[{"name":"Omaha, Nebraska"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nirav J.","family":"Mehta","sequence":"additional","affiliation":[{"name":"Omaha, Nebraska"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2002,1,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1099\/00221287-26-1-123"},{"key":"atypb2","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1099\/00207713-33-2-409","volume":"33","author":"Swings J.","year":"1983","journal-title":"Int J Syst Bacteriol"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(10)66684-2"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.48.2.365"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/128.Supplement_3.S771"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(78)90219-X"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1978.03630360049022"},{"key":"atypb8","first-page":"311","volume":"27","author":"Subbannayya K.","year":"1984","journal-title":"Ind J Pathol Microbiol."},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1987.00370090148025"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-199009000-00003"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/13.5.963"},{"key":"atypb12","first-page":"1170","volume":"91","author":"Jang TN","year":"1992","journal-title":"J Form Med Assoc"},{"key":"atypb13","first-page":"399","volume":"102","author":"Soriano V.","year":"1994","journal-title":"Med Clin"},{"key":"atypb14","first-page":"188","volume":"13","author":"Onate J.","year":"1995","journal-title":"Enfem Infecc Microbiol Clin"},{"key":"atypb15","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/23.6.1261"},{"key":"atypb16","doi-asserted-by":"publisher","DOI":"10.1016\/S0163-4453(98)92386-6"},{"key":"atypb17","first-page":"353","volume":"17","author":"Munter RG","year":"1998","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"atypb18","first-page":"1389","volume":"92","author":"Meimoun P.","year":"1999","journal-title":"A case report. 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