{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T17:47:15Z","timestamp":1777398435686,"version":"3.51.4"},"reference-count":27,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2004,7,1]],"date-time":"2004-07-01T00:00:00Z","timestamp":1088640000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Angiology"],"published-print":{"date-parts":[[2004,7]]},"abstract":"<jats:p>\n                    The etiology of Beh\u00e7et\u2019s disease, a systemic vasculitis, is unknown. Vascular involvement may be seen in 25% of patients with Beh\u00e7et\u2019s disease. Vasculitis make the prognosis of Beh\u00e7et's disease severe. The aim of this study is to examine the structural and functional changes and relations of these changes with progression and prognosis of Beh\u00e7et\u2019s disease. For this purpose, 40 patients with Beh\u00e7et\u2019s disease and 40 healthy volunteer control subjects were analyzed, additionally patients with Beh\u00e7et\u2019s disease were divided into 2 subgroups as those with vascular complications and those without vascular complications. Intima-media thickness and arterial distensibility were measured in all subjects with carotid artery ultrasonography. Carotid artery distensibility was significantly lower in the patient group compared to the control group (0.67 \u00b10.2, 0.93 \u00b10.4, p&lt;0.05), and carotid artery IMT was significantly higher (0.59 \u00b112, 0.80 \u00b10.11, p&lt;0.05). A statistically significant increase in IMT has been detected (0.77 \u00b111, 0.86 \u00b111, p&lt;0.05) in patients with Beh\u00e7et\u2019s disease with vascular involvement compared to patients with Beh\u00e7et\u2019s disease without vascular involvement, arterial distensibility in patients with vascular disease was similar with those who has no vascular disease (0.69 \u00b10.25, 0.63 \u00b10.25, p&gt;0.05). There was a significant negative linear regression between arterial distensibility and systolic blood pressure (SBP) (B=-1x10\n                    <jats:sup>-2<\/jats:sup>\n                    , p&lt;0.05), and a significant positive linear regression has also been found between IMT and SBP and diastolic blood pressure (DBP) and pulse pressure (PP) (B=6.8x10\n                    <jats:sup>-3<\/jats:sup>\n                    for SBP, p&lt;0.05, B=6.9x10\n                    <jats:sup>-3<\/jats:sup>\n                    for DBP, p&lt;0.05, B=6x10\n                    <jats:sup>-3<\/jats:sup>\n                    for PP, p&lt;0.05). As a result, IMT increases and AD decreases in patients with Beh\u00e7et\u2019s disease compared to results in the control group. Although more studies are required for this subject, use of noninvasive parameters such as IMT and AD, which reflect the structural and functional characteristics of vasculature, may be useful to define disease progression and subjects at high risk.\n                  <\/jats:p>","DOI":"10.1177\/000331970405500408","type":"journal-article","created":{"date-parts":[[2006,3,31]],"date-time":"2006-03-31T16:26:23Z","timestamp":1143822383000},"page":"413-419","source":"Crossref","is-referenced-by-count":38,"title":["Intima-Media Thickness and Arterial Distensibility in Beh\u00e7et\u2019s Disease"],"prefix":"10.1177","volume":"55","author":[{"given":"Sait","family":"Alan","sequence":"first","affiliation":[{"name":"Department of Cardiology, Dicle University School of Medicine, Diyarbakir, Turkey,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet S.","family":"Ulgen","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Dicle University School of Medicine, Diyarbakir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sedat","family":"Akdeniz","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Dicle University School of Medicine, Diyarbakir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bircan","family":"Alan","sequence":"additional","affiliation":[{"name":"Sevgi Hospital Department of Radiology Diyarbakir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nizamettin","family":"Toprak","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Dicle University School of Medicine, Diyarbakir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2004,7,1]]},"reference":[{"key":"atypb1","first-page":"37","volume-title":"Sixth International Conference of Beh\u00e7et\u2019s Disease","author":"Hamza M"},{"key":"atypb2","first-page":"38","volume-title":"Sixth International Conference of Beh\u00e7et\u2019s Disease","author":"Shafai N"},{"key":"atypb3","first-page":"213","volume":"34","author":"Gupta RC","year":"1978","journal-title":"Clin Exp Immunol"},{"key":"atypb4","first-page":"193","volume":"32","author":"Levinski RJ","year":"1978","journal-title":"Clin Exp Immunol"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(90)70179-L"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(89)90187-3"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1097\/00043798-199502000-00004"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.17.11.1330"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.18.5.618"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199011083231901"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1097\/00005344-199000151-00006"},{"key":"atypb12","first-page":"20","volume":"4","author":"Mercuri 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