{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T17:49:24Z","timestamp":1777398564084,"version":"3.51.4"},"reference-count":9,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Angiology"],"published-print":{"date-parts":[[2005,1]]},"abstract":"<jats:p>In patients treated for breast carcinoma, unilateral lymphedema of the upper limb is usual. However, to the authors\u2019 knowledge, lower limb lymphedema has never been reported as a complication of breast carcinoma therapy. They report here the first case of a radiation-induced constrictive pericarditis revealed by severe lower limbs lymphedema. A 60-year-old woman was treated for left breast carcinoma with quadrantectomy, axillary lymphadenectomy, and combined radio chemotherapy (60 grays). Three and a half years later she suffered from a diffuse and increasing lower limbs lymphedema, which became huge and disabling. Radiation-induced constrictive pericarditis was evidenced by right cardiac cavities catheterization. A dramatic improvement was rapidly obtained after pericardectomy. Histopathologic analysis of the pericardium did not reveal neoplastic cells. Radiation-induced constrictive pericarditis is usually responsible for lower limbs edema, but lymphedema is exceptional. This case highlights the need to search for a constrictive pericarditis also in the case of lower limbs lymphedema, particularly in a patient treated with mediastinal radiotherapy or combined radio chemotherapy.<\/jats:p>","DOI":"10.1177\/000331970505600118","type":"journal-article","created":{"date-parts":[[2006,3,31]],"date-time":"2006-03-31T16:26:23Z","timestamp":1143822383000},"page":"119-121","source":"Crossref","is-referenced-by-count":4,"title":["Severe Lower Limbs Lymphedema Following Breast Carcinoma Treatment Revealing Radiation-Induced Constrictive Pericarditis"],"prefix":"10.1177","volume":"56","author":[{"given":"B.","family":"Granel","sequence":"first","affiliation":[{"name":"Service de M\u00e9decine Interne, CHU Timone, Marseille"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Gaudy","sequence":"additional","affiliation":[{"name":"Service de M\u00e9decine Interne, CHU Timone, Marseille"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Serratrice","sequence":"additional","affiliation":[{"name":"Service de M\u00e9decine Interne, CHU Timone, Marseille"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicoleta","family":"Ene","sequence":"additional","affiliation":[{"name":"Service de M\u00e9decine Interne, CHU Timone, Marseille"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Mesana","sequence":"additional","affiliation":[{"name":"Service de Chirurgie Cardiaque, CHU Timone, Marseille"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. 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