{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T01:35:53Z","timestamp":1789868153437,"version":"4.0.1"},"reference-count":66,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2008,5,25]],"date-time":"2008-05-25T00:00:00Z","timestamp":1211673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Angiology"],"published-print":{"date-parts":[[2009,2]]},"abstract":"<jats:sec>\n                    <jats:title>Background.<\/jats:title>\n                    <jats:p>We investigated the time course and prognostic value of fibrinogen (Fib), C-reactive protein (CRP), interleukin-6 (IL-6), and ceruloplasmin (CP) in patients with severe unstable angina. Methods. All 4 substances were measured on admission and after 6, 12, 24, 48, and 72 hours, and after 7 days and 6 months in 40 patients with Braunwald's classification class IIIB unstable angina. Results. All recorded substances increased significantly; 15 patients had cardiovascular events during hospitalization and 11 patients during follow-up. The time course and the mean values of Fib, CRP, and IL-6 were similar in patients with and without complications both during hospitalization and follow-up. However, CP levels from 6 hours until 6 months were significantly higher in patients with complications during follow-up ( P &lt; .05). Conclusions. Fib, CRP, IL-6, and CP levels alter in patients with severe unstable angina. However, only CP levels were related to 12-month follow-up prognosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0003319708314249","type":"journal-article","created":{"date-parts":[[2008,4,3]],"date-time":"2008-04-03T20:25:56Z","timestamp":1207254356000},"page":"50-59","source":"Crossref","is-referenced-by-count":12,"title":["Ceruloplasmin is a Better Predictor of the Long-Term Prognosis Compared with Fibrinogen, CRP, and IL-6 in Patients with Severe Unstable Angina"],"prefix":"10.1177","volume":"60","author":[{"given":"Antonios","family":"Ziakas","sequence":"first","affiliation":[{"name":"1st Cardiology Department, AHEPA, University Hospital, Thessaloniki, Greece."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stavros","family":"Gavrilidis","sequence":"additional","affiliation":[{"name":"1st Cardiology Department, AHEPA, University Hospital, Thessaloniki, Greece."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Efthimia","family":"Souliou","sequence":"additional","affiliation":[{"name":"1st Cardiology Department, AHEPA, University Hospital, Thessaloniki, Greece."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Giannoglou","sequence":"additional","affiliation":[{"name":"1st Cardiology Department, AHEPA, University Hospital, Thessaloniki, Greece."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ioannis","family":"Stiliadis","sequence":"additional","affiliation":[{"name":"1st Cardiology Department, AHEPA, University Hospital, Thessaloniki, Greece."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haralambos","family":"Karvounis","sequence":"additional","affiliation":[{"name":"1st Cardiology Department, AHEPA, University Hospital, Thessaloniki, Greece."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Efthimiadis","sequence":"additional","affiliation":[{"name":"1st Cardiology Department, AHEPA, University Hospital, Thessaloniki, Greece."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sotirios","family":"Mochlas","sequence":"additional","affiliation":[{"name":"1st Cardiology Department, AHEPA, University Hospital, Thessaloniki, Greece."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Arvanitidou","family":"Vayona","sequence":"additional","affiliation":[{"name":"1st Cardiology Department, AHEPA, University Hospital, Thessaloniki, Greece."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Apostolos","family":"Hatzitolios","sequence":"additional","affiliation":[{"name":"1st Cardiology Department, AHEPA, University Hospital, Thessaloniki, Greece."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christos","family":"Savopoulos","sequence":"additional","affiliation":[{"name":"1st Cardiology Department, AHEPA, University Hospital, Thessaloniki, Greece."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ifigenia","family":"Pidonia","sequence":"additional","affiliation":[{"name":"1st Cardiology Department, AHEPA, University Hospital, Thessaloniki, Greece."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Parharidis","sequence":"additional","affiliation":[{"name":"1st Cardiology Department, AHEPA, 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