{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T21:23:30Z","timestamp":1790717010673,"version":"4.1.0"},"reference-count":37,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2009,4,26]],"date-time":"2009-04-26T00:00:00Z","timestamp":1240704000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Angiology"],"published-print":{"date-parts":[[2010,2]]},"abstract":"<jats:p>Objectives: Chronic inflammatory diseases are associated with an accelerated atherosclerotic process. Recent studies have discussed whether inflammatory bowel diseases (IBDs) can predict early atherosclerosis. We investigated this possibility. Methods: The study consisted of IBD cases (group 1, n = 40) and healthy persons (group 2, n = 40). The IBD group was selected so as not to have vascular disease or the presence of established major cardiovascular risk factors. Results: Group 1 cases showed a significant increase in carotid intima media thickness (cIMT; P = .01). Carotid artery stiffness was impaired in group 1 (P = .03) and high-sensitivity C-reactive protein (hsCRP), homeostasis model assessment of insulin resistance (HOMA-IR), and homocysteine (Hyc) were higher in group 1 patients (P = .02, P = .03, P = .05). Conclusions: Inflammatory bowel disease patients have an increased risk of early atherosclerosis as shown by greater values of cIMT, carotid artery stiffness, Hyc, hsCRP, and insulin resistance.<\/jats:p>","DOI":"10.1177\/0003319709333869","type":"journal-article","created":{"date-parts":[[2009,4,27]],"date-time":"2009-04-27T20:13:33Z","timestamp":1240863213000},"page":"198-204","source":"Crossref","is-referenced-by-count":65,"title":["Is Inflammatory Bowel Disease a Risk Factor for Early Atherosclerosis?"],"prefix":"10.1177","volume":"61","author":[{"given":"Necati","family":"Dagli","sequence":"first","affiliation":[{"name":"Department of Cardiology, First University, Medical School, Elazi\u011f, Turkey,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Orhan K.","family":"Poyrazoglu","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, , Medical School, Elazi\u011f, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Ferda Dagli","sequence":"additional","affiliation":[{"name":"Department of Pathology, First University, Medical School, Elazi\u011f, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatih","family":"Sahbaz","sequence":"additional","affiliation":[{"name":"Department of Internal Medicinen, First University, Medical School, Elazi\u011f, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilgin","family":"Karaca","sequence":"additional","affiliation":[{"name":"Department of Cardiology, First University, Medical School, Elazi\u011f, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Ali Kobat","sequence":"additional","affiliation":[{"name":"Department of Cardiology, First University, Medical School, Elazi\u011f, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ibrahim 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