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Women with PCOS received (1) conjugated estrogens and cyproterone acetate (n = 22), (2) 17\u03b2-estradiol and cyproterone acetate (n = 17), (3) ethinyl-estradiol and cyproterone acetate (high dose; n = 20), (4) ethinyl-estradiol plus cyproterone acetate (low dose; n = 12), or (5) ethinyl-estradiol plus desogetrel (n = 12). Both hsCRP and Hcy levels were measured at baseline and after 4, 7, and 12 months. The 17\u03b2-estradiol\/cyproterone acetate regime resulted in significant reduction of both hsCRP and Hcy levels (P &lt; .001). The other 4 regimes only resulted in a reduction of Hcy levels (P &lt; .001). In conclusion, the 17\u03b2-estradiol\/cyproterone acetate regime had the most favorable effects in women with PCOS regarding serum levels of hsCRP and Hcy.<\/jats:p>","DOI":"10.1177\/0003319709361198","type":"journal-article","created":{"date-parts":[[2010,4,15]],"date-time":"2010-04-15T20:25:57Z","timestamp":1271363157000},"page":"595-601","source":"Crossref","is-referenced-by-count":11,"title":["Serum High-Sensitivity C-Reactive Protein and Homocysteine Changes During Hormonal Therapy in Women With Polycystic Ovary Syndrome: A Prospective, Matched Study"],"prefix":"10.1177","volume":"61","author":[{"given":"Anastasios","family":"Makedos","sequence":"first","affiliation":[{"name":"Unit of Reproductive Endocrinology and Human Reproduction, Second Department of Obstetrics and Gynecology, Aristotle University of Thessaloniki, Greece,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dimitrios G.","family":"Goulis","sequence":"additional","affiliation":[{"name":"Unit of 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