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Circulating OxLDL showed a significant and independent association with the average cIMT of both carotid arteries but not with the absence or presence of \u22651 carotid atheroma plaques. Plasma OxLDL concentrations were associated with age, smoking, low-density lipoprotein-cholesterol, and triglycerides, independently of other variables. Our findings in an asymptomatic sample representative of the Spanish middle- and old-age population underscore the role of OxLDL in early atherosclerosis represented by the cIMT especially in older asymptomatic individuals, but this cannot be extended to more advanced atherosclerosis, represented by carotid plaques.<\/jats:p>","DOI":"10.1177\/0003319713488639","type":"journal-article","created":{"date-parts":[[2013,5,9]],"date-time":"2013-05-09T23:55:12Z","timestamp":1368143712000},"page":"357-362","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["LDL Oxidation and Its Association With Carotid Artery Intima-Media Thickness and Other Cardiovascular Risk Factors in a Sample of Spanish General Population"],"prefix":"10.1177","volume":"65","author":[{"given":"Pilar","family":"Calmarza","sequence":"first","affiliation":[{"name":"Service of Clinical Biochemistry, Hospital Universitario Miguel Servet, Zaragoza, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Mar\u00eda","family":"Trejo","sequence":"additional","affiliation":[{"name":"Service of Neurology, Research Unit, Complejo Asistencial, Burgos, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Lapresta","sequence":"additional","affiliation":[{"name":"Service of Preventive Medicine, Hospital Universitario Miguel Servet, Zaragoza, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pilar","family":"L\u00f3pez","sequence":"additional","affiliation":[{"name":"Service of Urgences, Research Unit, Complejo Asistencial, Burgos, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2013,5,9]]},"reference":[{"key":"bibr1-0003319713488639","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.272.34.20963"},{"key":"bibr2-0003319713488639","doi-asserted-by":"publisher","DOI":"10.1191\/096120300678828280"},{"key":"bibr3-0003319713488639","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.8.1.79"},{"key":"bibr4-0003319713488639","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2275(20)37250-3"},{"key":"bibr5-0003319713488639","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.103.15.1930"},{"key":"bibr6-0003319713488639","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.13.3.331"},{"key":"bibr7-0003319713488639","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.98.15.1487"},{"key":"bibr8-0003319713488639","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.20.10.2243"},{"key":"bibr9-0003319713488639","doi-asserted-by":"publisher","DOI":"10.1038\/35025203"},{"key":"bibr10-0003319713488639","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(01)00238-0"},{"key":"bibr11-0003319713488639","doi-asserted-by":"publisher","DOI":"10.1136\/heart.84.3.238"},{"key":"bibr12-0003319713488639","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.0000021150.63480.CD"},{"key":"bibr13-0003319713488639","doi-asserted-by":"publisher","DOI":"10.1007\/BF02254440"},{"key":"bibr14-0003319713488639","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.108.167346"},{"key":"bibr15-0003319713488639","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.21.5.844"},{"key":"bibr16-0003319713488639","doi-asserted-by":"crossref","unstructured":"van den Oord SC, Sijbrands EJ, Ten Kate GL, Carotid intima-media thickness for cardiovascular risk assessment: Systematic review and meta-analysis [published online January 25, 2013]. 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