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In light of the inclusion of TMZ in the current guidelines on the management of stable CHD, we reviewed the published literature on TMZ, focusing mainly its effects on patients with stable angina and HF. According to the published literature, there is sufficient evidence to support the addition of this agent in the treatment of symptomatic patients with stable angina.<\/jats:p>","DOI":"10.1177\/0003319714530040","type":"journal-article","created":{"date-parts":[[2014,4,9]],"date-time":"2014-04-09T23:12:11Z","timestamp":1397085131000},"page":"204-210","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":28,"title":["Trimetazidine and Cardioprotection"],"prefix":"10.1177","volume":"66","author":[{"given":"Konstantinos","family":"Tsioufis","sequence":"first","affiliation":[{"name":"First Cardiology Clinic, Hippokration Hospital, University of Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Andrikopoulos","sequence":"additional","affiliation":[{"name":"Cardiology Department, Henry Dunant Hospital, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Athanasios","family":"Manolis","sequence":"additional","affiliation":[{"name":"Cardiology Department, Asklepeion General Hospital, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2014,4,8]]},"reference":[{"key":"bibr1-0003319714530040","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/eht296"},{"key":"bibr2-0003319714530040","doi-asserted-by":"publisher","DOI":"10.1097\/00019501-200304000-00010"},{"issue":"9","key":"bibr3-0003319714530040","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1111\/j.1742-1241.1968.tb04953.x","volume":"22","author":"Brodbin P","year":"1968","journal-title":"Br J Clin Pract"},{"key":"bibr4-0003319714530040","unstructured":"Questions and answers on the review of medicines containing trimetazidine (20 mg tablets, 35 mg modified release tablet and 20 mg\/ml oral solution). http:\/\/www.ema.europa.eu\/docs\/en_GB\/document_library\/Referrals_document\/Trimetazidine_31\/WC500129195.pdf. 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