{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T18:24:38Z","timestamp":1777400678276,"version":"3.51.4"},"reference-count":34,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2015,9,2]],"date-time":"2015-09-02T00:00:00Z","timestamp":1441152000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Angiology"],"published-print":{"date-parts":[[2016,7]]},"abstract":"<jats:p>We investigated whether serum bilirubin level (a marker of heme oxygenase activity) is a predictor of thrombus burden in patients with acute myocardial infarction. Patients (n = 229; male 72.9%; mean age 63 \u00b1 13.4 years) who were admitted with ST-segment elevation myocardial infarction (STEMI) were enrolled. Patients were divided into 2 groups. Group 1 was defined as low thrombus burden and group 2 was defined as high thrombus burden. Patients with high thrombus burden had higher total bilirubin levels (14.4 [4.3-22.9] vs 7.7 [2.4-20.3] \u00b5mol\/L, P \u2264 .001), (0.84 [0.25-1.34] vs 0.45 [0.14-1.19] mg\/dL P \u2264 .001) and direct bilirubin levels (3.1 [2.1-8.4] vs 1.7 [0.5-6.5] \u00b5mol\/L, P \u2264 .001), (0.18 [0.03-0.49] vs 0.10 [0.03-0.38] mg\/dL, P \u2264 .001). At multivariate analysis, total bilirubin (odds ratio: 1.05, 95% confidence interval: 1.03-1.08, P \u2264 .001) was the independent predictor of high thrombus burden. In conclusion, total bilirubin level is independently associated with high thrombus burden in patients with STEMI.<\/jats:p>","DOI":"10.1177\/0003319715603899","type":"journal-article","created":{"date-parts":[[2015,9,3]],"date-time":"2015-09-03T20:14:05Z","timestamp":1441311245000},"page":"565-570","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":29,"title":["Bilirubin Levels and Thrombus Burden in Patients With ST-Segment Elevation Myocardial Infarction"],"prefix":"10.1177","volume":"67","author":[{"given":"Hikmet","family":"Hamur","sequence":"first","affiliation":[{"name":"Department of Cardiology, Faculty of Medicine, Erzincan University, Erzincan, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hakan","family":"Duman","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Faculty of Medicine, Recep Tayyip Erdo\u011fan University, Rize, 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