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This study evaluated the antianginal efficacy and effect of ivabradine treatment on quality of life (QOL) in patients with CAD and history of coronary revascularization. This is a post hoc analysis (926 post-revascularization patients) of a prospective, noninterventional study, which included 2403 patients with CAD and stable angina. The data were recorded at baseline, at 1 month and 4 months after inclusion. After ivabradine administration, mean number of anginal events decreased from 2.2 \u00b1 2.3 (median: 2.0, minimum: 0.0, maximum: 21.0, range: 21.0) to 0.3 \u00b1 0.6 (median: 0.0, minimum: 0.0, maximum: 7.0, range: 7.0) times\/week ( P &lt; .001), while nitroglycerin consumption decreased from 1.5 \u00b1 2.2 (median: 1.0, minimum: 0.0, maximum: 20.0, range: 20.0) to 0.1 \u00b1 0.4 times\/week (median: 0.0, minimum: 0.0, maximum: 5.0, range: 5.0; P &lt; .001). Quality of life improved at study completion compared to baseline ( P &lt; .001). Ivabradine addition on top of optimal individualized dose of \u03b2-blockers is associated with decreased anginal events and improvement in QOL in patients with stable angina and history of coronary revascularization.<\/jats:p>","DOI":"10.1177\/0003319716630499","type":"journal-article","created":{"date-parts":[[2016,3,9]],"date-time":"2016-03-09T20:18:19Z","timestamp":1457554699000},"page":"10-18","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Antianginal Efficacy of Ivabradine in Patients With History of Coronary Revascularization"],"prefix":"10.1177","volume":"68","author":[{"given":"J.","family":"Zarifis","sequence":"first","affiliation":[{"name":"Cardiology Department, George Papanikolaou General Hospital, Thessaloniki, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Grammatikou","sequence":"additional","affiliation":[{"name":"Medical Department, Servier Hellas Pharmaceuticals Ltd, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Kallistratos","sequence":"additional","affiliation":[{"name":"Medical Department, Servier Hellas Pharmaceuticals Ltd, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Katsivas","sequence":"additional","affiliation":[{"name":"First Cardiology Department, Korgialeneio-Benakeio E.E.S. 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