{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T18:27:26Z","timestamp":1777400846602,"version":"3.51.4"},"reference-count":33,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2016,11,4]],"date-time":"2016-11-04T00:00:00Z","timestamp":1478217600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Angiology"],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:p>We evaluated the effect of long-term administration of nicorandil on endothelial function of the radial artery in patients with angina undergoing elective transradial coronary intervention (TRI). A total of 127 patients were randomly assigned to nicorandil (standard medication plus nicorandil 5 mg twice daily, n = 64) or control group (standard medication except nicorandil, n = 63) immediately after TRI procedure. Radial artery diameter (RAD), flow-mediated dilation (FMD), and nitroglycerin-mediated dilation (NMD) of radial artery were measured 1 day before TRI as well as 1 day and 3 months after TRI by Ultrasound-Doppler. No significant difference was observed in the baseline RAD, FMD, and NMD between the 2 groups (all P &gt; .05). In cannulated arm, at 3-month follow-up, RAD in nicorandil group was much larger than that in the control group (2.78 \u00b1 0.27 mm vs 2.61 \u00b1 0.30 mm, P = .001). Besides, FMD and NMD were much higher in nicorandil group than those in the control group (10.38% \u00b1 2.43% vs 6.81% \u00b1 1.86%; 15.94% \u00b1 6.28% vs 10.46% \u00b1 5.37%, respectively, all Ps &lt; .001). In conclusion, long-term administration of nicorandil after TRI could improve the endothelial function of the cannulated radial artery.<\/jats:p>","DOI":"10.1177\/0003319716675720","type":"journal-article","created":{"date-parts":[[2016,11,4]],"date-time":"2016-11-04T21:09:36Z","timestamp":1478293776000},"page":"633-639","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Effect of Long-Term Administration of Nicorandil on Endothelial Function of the Radial Artery in Patients With Angina Undergoing Transradial Percutaneous Coronary Intervention"],"prefix":"10.1177","volume":"68","author":[{"given":"Yanming","family":"Fan","sequence":"first","affiliation":[{"name":"Department of Cardiology, Second Hospital of Hebei Medical University, Shijiazhuang, People\u2019s Republic of 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