{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T13:36:45Z","timestamp":1785332205293,"version":"3.55.0"},"reference-count":28,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2017,1,5]],"date-time":"2017-01-05T00:00:00Z","timestamp":1483574400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Angiology"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:p>\n                    The utility of the ear crease sign, anterior tragal crease (ATC), as a marker of atherosclerosis is yet to be established. The intima\u2013media thickness of the common carotid artery (IMT-CCA) has been used as a noninvasive surrogate marker for atherosclerosis. History of traditional risk factors for atherosclerosis was obtained from 147 volunteers; ear examination was also performed and venous blood was drawn for laboratory analysis. The volunteers then underwent an ultrasonography measurement of the IMT-CCA. In univariate analysis, presence of ATC, age, underlying hypertension, diabetes mellitus, ischemic heart disease, cerebrovascular disease, cigarette smoking, low-density lipoprotein, and high-sensitivity C-reactive protein were significantly associated with the IMT-CCA. Further multivariate analysis confirmed a significant association between the presence of ATC and IMT-CCA, when adjusted for other factors (adjusted \u03b2\n                    <jats:sub>ATC<\/jats:sub>\n                    = .010, 95% confidence interval: 0.0021-0.019). Anterior tragal crease is a potential clinical sign that can predict atherosclerosis. The sign is easily recognizable and may help health-care professionals to identify those at risk of atherosclerosis, especially in people with no clinical signs of the disease.\n                  <\/jats:p>","DOI":"10.1177\/0003319716685481","type":"journal-article","created":{"date-parts":[[2017,1,7]],"date-time":"2017-01-07T09:55:28Z","timestamp":1483782928000},"page":"683-687","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Anterior Tragal Crease Is Associated With Atherosclerosis: A Study Evaluating Carotid Artery Intima\u2013Media Thickness"],"prefix":"10.1177","volume":"68","author":[{"given":"Pawinee","family":"Rerknimitr","sequence":"first","affiliation":[{"name":"Division of Dermatology, Department of Medicine, Faculty of Medicine, Allergy and Clinical Immunology Research Group, Chulalongkorn University, Bangkok, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Korbkarn","family":"Pongpairoj","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Department of Medicine, Faculty of Medicine, Allergy and Clinical Immunology Research Group, Chulalongkorn University, Bangkok, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chanat","family":"Kumtornrat","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Department of Medicine, Faculty of Medicine, Allergy and Clinical Immunology Research Group, Chulalongkorn University, Bangkok, Thailand"},{"name":"Dermatology Unit, Department of Medicine, King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ratchathorn","family":"Panchaprateep","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Department of Medicine, Faculty of Medicine, Allergy and Clinical Immunology Research Group, Chulalongkorn University, Bangkok, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cameron P.","family":"Hurst","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Center for Excellence in Biostatistics, Chulalongkorn University, Bangkok, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aurauma","family":"Chutinet","sequence":"additional","affiliation":[{"name":"Division of Neurology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pravit","family":"Asawanonda","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Department of Medicine, Faculty of Medicine, Allergy and Clinical Immunology Research Group, Chulalongkorn University, Bangkok, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nijasri C.","family":"Suwanwela","sequence":"additional","affiliation":[{"name":"Division of Neurology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2017,1,5]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2016.03.205"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a116963"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2014.04.025"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-09-0141"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2006.08.042"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1590\/S1807-59322010001200016"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1177\/0003319713479651"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.5114\/aoms.2015.56340"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.01.006"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(92)93147-F"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2006.03.002"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2009.03481.x"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2006.09.001"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2011-300747"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.113.000087"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.1177\/0003319714522849"},{"key":"e_1_3_4_18_2","doi-asserted-by":"publisher","DOI":"10.2174\/0929867322666150415125828"},{"key":"e_1_3_4_19_2","unstructured":"R Core Team. 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