{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T18:17:06Z","timestamp":1777400226596,"version":"3.51.4"},"reference-count":21,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2017,7,10]],"date-time":"2017-07-10T00:00:00Z","timestamp":1499644800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Angiology"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:p>Takotsubo cardiomyopathy (TC) is a life-threatening syndrome with ambiguous pathophysiology. The interdependency between heart failure and kidney failure (KF) is well established, but the influence of KF on TC outcome is not known. This single-center cohort from January 2003 to September 2015 consisted of 114 consecutive patients with TC. They were divided into 2 groups according to the presence (n = 32, 29.6%) or absence (n = 76, 70.3%) of KF. The end point of this retrospective study was a composite of in-hospital events, all-cause mortality, rehospitalization due to heart failure, stroke, and recurrence of TC (mean follow-up: 5 years). Although there were no differences in baseline characteristics between patients with\/without KF, we found a significantly higher mortality rate in those with KF, 1 (7.9% vs 21.8%, P &lt; .05), 2 (11.8% vs 31.5%, P &lt; .05), and 5 years (22.3% vs 43.7%, P &lt; .05) after the index event. There were no differences in life-threatening arrhythmias, cardiogenic shock, cardiopulmonary resuscitation, and thromboembolic events in both groups at the index event. Patients with TC and KF have a much worse long-term prognosis. This is clinically relevant, but the mechanisms responsible remain to be determined.<\/jats:p>","DOI":"10.1177\/0003319717718978","type":"journal-article","created":{"date-parts":[[2017,12,31]],"date-time":"2017-12-31T12:03:26Z","timestamp":1514721806000},"page":"130-135","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Takotsubo Cardiomyopathy: Another Form of Cardiorenal Syndrome"],"prefix":"10.1177","volume":"69","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8861-9809","authenticated-orcid":false,"given":"Verena","family":"Bill","sequence":"first","affiliation":[{"name":"First Department of Medicine Cardiology, University Medical Centre Mannheim (UMM), Faculty of Medicine Mannheim, University of Heidelberg, Mannheim, Germany"},{"name":"DZHK (German Center for Cardiovascular Research) Partner Site Mannheim, Mannheim, 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