{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T18:18:15Z","timestamp":1777400295467,"version":"3.51.4"},"reference-count":29,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2017,12,12]],"date-time":"2017-12-12T00:00:00Z","timestamp":1513036800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Angiology"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:p>Resting heart rate (RHR) is associated with arterial stiffness, inflammation, and cardiovascular (CV) and all-cause mortality in the general population and in patients at high CV risk. We assessed the association of RHR with arterial stiffness and low-grade inflammation (LGI) in a cross-sectional study that included 101 women with systemic lupus erythematosus (SLE) without a history of CV disease or arrhythmia or who were under treatment that may cause bradycardia. Pulse wave velocity (PWV; a measure of arterial stiffness), RHR, and markers of LGI (ie, C-reactive protein, fibrinogen, erythrocyte sedimentation rate, insulin, and homeostatic model assessment index) were measured. The patients with the highest RHR (quartile 4; mean RHR = 87.2 bpm) had a PWV 0.61 m\/s (95% confidence interval [CI]: 0.08-1.14; P = .024) greater than patients with the lowest RHR (quartile 1; RHR = 63.0 bpm), independent of age, systolic blood pressure, disease activity, smoking, and being physically inactive. Similarly, patients with the highest RHR (quartile 4) showed a significantly less favorable clustered LGI index than patients in quartile 1 ( b = .58; 95% CI: 0.212-0.948; P = .002). Higher RHR is associated with greater arterial stiffness and LGI in women with SLE. Further research to determine the prognostic value of RHR in this population is warranted.<\/jats:p>","DOI":"10.1177\/0003319717746525","type":"journal-article","created":{"date-parts":[[2017,12,13]],"date-time":"2017-12-13T04:03:37Z","timestamp":1513137817000},"page":"672-676","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Association of Resting Heart Rate With Arterial Stiffness and Low-Grade Inflammation in Women With Systemic Lupus Erythematosus"],"prefix":"10.1177","volume":"69","author":[{"given":"Jos\u00e9 Antonio","family":"Vargas-Hitos","sequence":"first","affiliation":[{"name":"Systemic Autoimmune Diseases Unit, Department of Internal Medicine, Virgen de las Nieves University Hospital, Granada, Spain"},{"name":"*\u2009Dr Vargas-Hitos and Dr Soriano-Maldonado contributed equally to this work."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alberto","family":"Soriano-Maldonado","sequence":"additional","affiliation":[{"name":"Department of Education, Faculty of Education Sciences, University of Almer\u00eda, Almer\u00eda, Spain"},{"name":"SPORT Research Group (CTS-1024), CERNEP Research Center, University of Almer\u00eda, Almer\u00eda, Spain"},{"name":"*\u2009Dr Vargas-Hitos and Dr Soriano-Maldonado contributed equally to this work."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josefa","family":"Mart\u00ednez-Bordonado","sequence":"additional","affiliation":[{"name":"Systemic Autoimmune Diseases Unit, Department of Internal Medicine, Virgen de las Nieves University Hospital, Granada, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabel","family":"S\u00e1nchez-Bern\u00e1","sequence":"additional","affiliation":[{"name":"Systemic Autoimmune Diseases Unit, Department of Internal Medicine, Virgen de las Nieves 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