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In this study, we investigated whether serum albumin level is a useful predictor of long-term mortality in patients with UAP\/NSTEMI. Consecutive patients (n = 403) who were hospitalized with a diagnosis of UAP\/NSTEMI were included in the study. Patients were divided into 2 groups based on the presence of hypoalbuminemia and the relationship between hypoalbuminemia and mortality was analyzed. Hypoalbuminemia was detected in 34% of the patients. The median follow-up period was 35 months (up to 45 months). Long-term mortality rate was 32% in the hypoalbuminemia group and 8.6% in the group with normal serum albumin levels ( P &lt; .001). On multivariate analysis, hypoalbuminemia, decreased left ventricular ejection fraction, and increased age were found to be independent predictors of mortality ( P &lt; .05). The cutoff value of 3.10 g\/dL for serum albumin predicted mortality with a sensitivity of 74% and specificity of 67% (receiver-operating characteristic area under curve: 0.753, 95% CI: 0.685-0.822). All-cause long-term mortality rates were significantly increased in patients with hypoalbuminemia. On-admission albumin level was an independent predictor of mortality in patients with UAP\/NSTEMI.<\/jats:p>","DOI":"10.1177\/0003319720941747","type":"journal-article","created":{"date-parts":[[2020,7,17]],"date-time":"2020-07-17T08:02:49Z","timestamp":1594972969000},"page":"903-908","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":32,"title":["Prognostic Significance of Serum Albumin in Patients With Acute Coronary Syndrome"],"prefix":"10.1177","volume":"71","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1992-7848","authenticated-orcid":false,"given":"Nihat","family":"Polat","sequence":"first","affiliation":[{"name":"Department of Cardiology, Dicle University School of Medicine, Diyarbakir, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustafa","family":"Oylumlu","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Dicle University School of Medicine, Diyarbakir, 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