{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T18:22:06Z","timestamp":1777400526208,"version":"3.51.4"},"reference-count":28,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2020,8,6]],"date-time":"2020-08-06T00:00:00Z","timestamp":1596672000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Angiology"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:p>Angiotensin-converting enzyme inhibitor (ACEi) and angiotensin II receptor blockers (ARB) showed comparable survival results in patients with heart failure (HF) and reduced left ventricular ejection fraction (LVEF). However, there is lack of evidence of the comparative effectiveness in preserved LVEF patients after an acute coronary syndrome (ACS). The aim of this study was to evaluate whether the selection between ACEi and ARB in preserved LVEF after an ACS confers a prognostic benefit, based on real life results. We analyzed a cohort of 3006 contemporary patients with LVEF \u226540% after an ACS. A propensity score matching and Cox regression analysis were performed to assess the association between treatment and events (death, acute myocardial infarction [AMI], HF, and combined event) for a mean follow-up of 3.6 \u00b1 2.1 years. We found no significant differences between ACEi\/ARB for all-cause mortality (hazard ratio [HR] for ARB: 0.95, 95% CI: 0.70-1.29), AMI (HR for ARB: 1.34, 95% CI: 0.95-1.89), HF (HR for ARB: 1.11, 95% CI: 0.85-1.45), or combined end point (death, AMI and HF: HR for ARB: 1.14, 95% CI: 0.92-1.40). In conclusion, there are no prognostic differences between the use of ACEi and ARB in patients with LVEF \u226540% after ACS. Further prospective studies are needed to confirm our results.<\/jats:p>","DOI":"10.1177\/0003319720946971","type":"journal-article","created":{"date-parts":[[2020,8,6]],"date-time":"2020-08-06T09:40:33Z","timestamp":1596706833000},"page":"886-893","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Angiotensin-Converting Enzyme Inhibitors Versus Angiotensin II Receptor Blockers in Acute Coronary Syndrome and Preserved Ventricular Ejection Fraction"],"prefix":"10.1177","volume":"71","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6549-4994","authenticated-orcid":false,"given":"Mar\u00eda","family":"Cesp\u00f3n-Fern\u00e1ndez","sequence":"first","affiliation":[{"name":"Cardiology Department, University Hospital \u00c1lvaro Cunqueiro, Vigo, Pontevedra, Spain"},{"name":"Clinical Research in Medicine, University of Santiago de Compostela, Santiago de Compostela, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergio","family":"Raposeiras-Roub\u00edn","sequence":"additional","affiliation":[{"name":"Cardiology Department, University Hospital \u00c1lvaro Cunqueiro, Vigo, Pontevedra, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emad","family":"Abu-Assi","sequence":"additional","affiliation":[{"name":"Cardiology Department, University Hospital \u00c1lvaro Cunqueiro, Vigo, Pontevedra, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabel Mu\u00f1oz","family":"Pousa","sequence":"additional","affiliation":[{"name":"Cardiology Department, University Hospital \u00c1lvaro Cunqueiro, Vigo, Pontevedra, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Berenice Caneiro","family":"Queija","sequence":"additional","affiliation":[{"name":"Cardiology Department, University Hospital \u00c1lvaro Cunqueiro, Vigo, Pontevedra, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafael Jos\u00e9 Cobas","family":"Paz","sequence":"additional","affiliation":[{"name":"Cardiology Department, University Hospital \u00c1lvaro Cunqueiro, Vigo, Pontevedra, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pablo Dom\u00ednguez","family":"Erquicia","sequence":"additional","affiliation":[{"name":"Cardiology Department, University Hospital \u00c1lvaro Cunqueiro, Vigo, Pontevedra, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis Manuel Dom\u00ednguez","family":"Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Cardiology Department, University Hospital \u00c1lvaro Cunqueiro, Vigo, Pontevedra, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena L\u00f3pez","family":"Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Cardiology Department, University Hospital \u00c1lvaro Cunqueiro, Vigo, Pontevedra, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Casti\u00f1eira","family":"Busto","sequence":"additional","affiliation":[{"name":"Cardiology Department, University Hospital \u00c1lvaro Cunqueiro, Vigo, Pontevedra, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saleta Fern\u00e1ndez","family":"Barbeira","sequence":"additional","affiliation":[{"name":"Cardiology Department, University Hospital \u00c1lvaro Cunqueiro, Vigo, Pontevedra, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e9s \u00cd\u00f1iguez","family":"Romo","sequence":"additional","affiliation":[{"name":"Cardiology Department, University Hospital \u00c1lvaro Cunqueiro, Vigo, Pontevedra, 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