{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T04:05:09Z","timestamp":1787976309139,"version":"build-2784847793"},"reference-count":32,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2021,8,28]],"date-time":"2021-08-28T00:00:00Z","timestamp":1630108800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Angiology"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:p>We investigated the predictors, aetiology and long-term outcomes of acute kidney injury (AKI) following urgent percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS). Acute kidney injury occurred in 198 (7.2%) of 2917 patients: 14.1% of AKI cases were attributed to cardiogenic shock and 5.1% were classified as atheroembolic renal disease (AERD). Significant risk factors for AKI included age (odds ratio [OR] 1.05, 95% confidence limits [CI] 1.03-1.06), diabetes (OR 1.73, 95% CI 1.20-2.47), hypertension (OR 1.43, 95% CI 1.03-2.00), heart failure (OR 3.01, 95% CI 1.58-5.57), femoral access (OR 1.50, 95% CI 1.03-2.15), cardiogenic shock (OR 2.03, 95% CI 1.19-3.37) and ST-elevation myocardial infarction (STEMI) (OR 3.89, 95% CI 2.80-5.47). One-year mortality after AERD was 44.4% and renal replacement therapy (RRT) requirement 22.2% (compared with mortality 33.3% and RRT requirement 7.4%, respectively, in all other AKI patients). Mortality at 1 year was associated with AKI (OR 4.33, 95% CI 2.89-6.43), age (OR 1.08, 95% CI 1.06-1.09), heart failure (OR 1.92, 95% CI 1.05-3.44), femoral access (OR 2.05, 95% CI 1.41-2.95) and cardiogenic shock (OR 3.63, 95% CI 2.26-5.77). Acute kidney injury after urgent PCI is strongly associated with worse outcomes. Atheroembolic renal disease has a poor outcome and a high likelihood of long-term RRT requirement.<\/jats:p>","DOI":"10.1177\/00033197211040375","type":"journal-article","created":{"date-parts":[[2021,8,28]],"date-time":"2021-08-28T09:01:48Z","timestamp":1630141308000},"page":"139-145","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":18,"title":["Acute Kidney Injury Following Percutaneous Coronary Intervention for Acute Coronary Syndrome: Incidence, Aetiology, Risk Factors and Outcomes"],"prefix":"10.1177","volume":"73","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3478-0407","authenticated-orcid":false,"given":"Elliott J","family":"Carande","sequence":"first","affiliation":[{"name":"Swansea Bay University Health Board, Morriston Hospital, Swansea, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen","family":"Brown","sequence":"additional","affiliation":[{"name":"Swansea Bay University Health Board, Morriston Hospital, Swansea, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Jackson","sequence":"additional","affiliation":[{"name":"Swansea Bay University Health Board, Morriston Hospital, Swansea, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5707-720X","authenticated-orcid":false,"given":"Nicholas","family":"Maskell","sequence":"additional","affiliation":[{"name":"Swansea Bay University Health Board, Morriston Hospital, Swansea, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Loukas","family":"Kouzaris","sequence":"additional","affiliation":[{"name":"Swansea University Medical School, Swansea, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giles","family":"Greene","sequence":"additional","affiliation":[{"name":"Public Health Wales, Cardiff, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashraf","family":"Mikhail","sequence":"additional","affiliation":[{"name":"Swansea Bay University Health Board, Morriston Hospital, Swansea, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel R","family":"Obaid","sequence":"additional","affiliation":[{"name":"Swansea Bay University Health Board, Morriston Hospital, Swansea, UK"},{"name":"Swansea University Medical School, Swansea, 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