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We hypothesized that a correlation would be observed between the clinical estimation of ischemia severity with exercise transcutaneous oximetry (Ex-TcpO2) and lactate increase. A prospective study was performed among 377 patients with arterial claudication. We recorded age, sex, ABI, body mass index (BMI), systolic arterial blood pressure (SBP), and glycemia. Capillary blood lactate was measured at rest and 3\u00a0min after a constant load treadmill test. We recorded maximum walking time (MWT), heart rate (HRmax), the sum of minimal decrease from oxygen values for buttocks, thighs and calves Ex-TcpO2 (DROPmin), as well as the amplitude of chest-TcpO2 decrease. A multilinear regression model was used to assess the variables associated with lactate increase. BMI, SBP, HRmax, the amplitude of decrease in chest-TcpO2 and DROPmin, but not age, sex, ABI, MWT, diabetes mellitus nor glycemia, were significantly associated to lactate increase in the model. Because it accounts for the severity and diffusion of lower-limb exercise-induced ischemia and detects exercise induced hypoxemia, TcpO2 may be preferable to ABI or MWT to estimate the metabolic consequences of walking in claudicants.<\/jats:p>","DOI":"10.1177\/00033197221112132","type":"journal-article","created":{"date-parts":[[2022,7,11]],"date-time":"2022-07-11T14:24:05Z","timestamp":1657549445000},"page":"526-535","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Exercise Oximetry Correlates Better With Exercise-Induced Lactate Increase, than Ankle Brachial Index or Walking Time, in Vascular Claudicants"],"prefix":"10.1177","volume":"74","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7070-5749","authenticated-orcid":false,"given":"Wends\u00e8ndat\u00e9 Yves","family":"Sempor\u00e9","sequence":"first","affiliation":[{"name":"Centre MURAZ, National Institute of Public Health, Bobo Dioulasso, Burkina Faso"},{"name":"MitoVasc Institute UMR CNRS 6015 \/ INSERM 1083, Angers, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeanne","family":"Hersant","sequence":"additional","affiliation":[{"name":"MitoVasc Institute UMR CNRS 6015 \/ INSERM 1083, Angers, France"},{"name":"Vascular Medicine, University Hospital of Angers, Pays de la Loire, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre","family":"Ramondou","sequence":"additional","affiliation":[{"name":"MitoVasc Institute UMR CNRS 6015 \/ INSERM 1083, Angers, France"},{"name":"Vascular Medicine, University Hospital of Angers, Pays de la Loire, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean Fran\u00e7ois","family":"Hamel","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, University Hospital of Angers, Pays de la Loire, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7053-2801","authenticated-orcid":false,"given":"Pierre","family":"Abraham","sequence":"additional","affiliation":[{"name":"MitoVasc Institute UMR CNRS 6015 \/ INSERM 1083, Angers, France"},{"name":"Vascular Medicine, University Hospital of Angers, Pays de la Loire, France"},{"name":"Sports Medicine, University Hospital of Angers, Pays de la Loire, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samir","family":"Henni","sequence":"additional","affiliation":[{"name":"Vascular Medicine, University Hospital of Angers, Pays de la Loire, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,7,11]]},"reference":[{"key":"bibr1-00033197221112132","doi-asserted-by":"publisher","DOI":"10.1177\/1358863X08089277"},{"key":"bibr2-00033197221112132","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)61249-0"},{"key":"bibr3-00033197221112132","doi-asserted-by":"publisher","DOI":"10.1053\/euhj.1998.1394"},{"key":"bibr4-00033197221112132","first-page":"150","volume":"31","author":"Falkensammer J","year":"2012","journal-title":"Int Angiol"},{"key":"bibr5-00033197221112132","first-page":"181","volume":"18","author":"Maass U","year":"1989","journal-title":"Vasa"},{"key":"bibr6-00033197221112132","doi-asserted-by":"publisher","DOI":"10.1007\/BF01721684"},{"key":"bibr7-00033197221112132","first-page":"H395","volume":"257","author":"Fellmann N","year":"1989","journal-title":"Am J Physiol"},{"key":"bibr8-00033197221112132","doi-asserted-by":"publisher","DOI":"10.1007\/BF00943373"},{"key":"bibr9-00033197221112132","unstructured":"Rodericks RK. 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