{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T16:42:51Z","timestamp":1779208971802,"version":"3.51.4"},"reference-count":24,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2022,9,2]],"date-time":"2022-09-02T00:00:00Z","timestamp":1662076800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"the Geriatric health Research Project of Jiangsu Province","award":["LK2021006"],"award-info":[{"award-number":["LK2021006"]}]},{"name":"Chinese Medicine Science and Technology Development Program of Jiangsu Province","award":["MS2021096"],"award-info":[{"award-number":["MS2021096"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Angiology"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:p>The present study explored the relationship between the ankle-brachial index (ABI) (&gt;.9) and all-cause or cardio-cerebrovascular mortality. Participant details were obtained from the National Health and Nutrition Examination Survey 1999\u20132004. The association between baseline ABI and the risk of mortality was evaluated by a priori defined quartile categories and on a continuous scale (per .1-unit change) with Cox regression models adjusted for demographic and traditional risk factors. A total of 7087 individuals (age: 59.6 \u00b1 12.8\u00a0years) were included; 3612 (51.0%) were male. After an average follow-up of 12.2 years, 1926 deaths occurred. Kaplan\u2013Meier analysis showed that the lowest ABI quartile (&lt;1.06) was associated with the highest risk of all-cause, cardio-cerebrovascular and cancer mortality (all P &lt; .001). However, after adjusting for potential confounders, ABI ranging between 1.06 and 1.12 was associated with the lowest risk of all-cause mortality (hazard ratio .88, 95% confidence interval .78\u20131.00, P &lt; .05) compared with the reference group (&lt;1.06). Besides, splines showed the relationship was nonlinear ( P &lt; .05) and the inflection point was 1.11. In conclusion, the level of ABI associated with the lowest risk of all-cause mortality was 1.11, under which a lower ABI was independently associated with an increased risk of all-cause mortality.<\/jats:p>","DOI":"10.1177\/00033197221121016","type":"journal-article","created":{"date-parts":[[2022,9,2]],"date-time":"2022-09-02T06:43:59Z","timestamp":1662101039000},"page":"649-656","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["Predictive Value of the Ankle-Brachial Index for All-Cause and Cardio-Cerebrovascular Mortality"],"prefix":"10.1177","volume":"74","author":[{"given":"Chang","family":"Xu","sequence":"first","affiliation":[{"name":"Department of Neurology, Geriatric Hospital of Nanjing Medical University, Jiangsu Province Official Hospital, Nanjing, China"},{"name":"Cognitive Impairment Research Institute of Geriatric Hospital of Nanjing Medical University, Jiangsu Province Official Hospital, 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