{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T18:32:55Z","timestamp":1777401175946,"version":"3.51.4"},"reference-count":21,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[2023,2,8]],"date-time":"2023-02-08T00:00:00Z","timestamp":1675814400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100017046","name":"School of Medicine, University of Maryland","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100017046","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Angiology"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:p>\n                    Intraoperative computed tomography (CT) imaging with endovascular delivery of intra-arterial (IA) contrast could potentially provide higher attenuation with lower contrast volumes than intravenous (IV) administration. We aimed to compare IA and IV contrast use for organ-specific CT abdominal imaging. Five anesthetized swine had external jugular and brachial artery access with ascending aortic pigtail placement. An IV protocol was 100\u00a0mL at 5\u00a0mL\/sec over 20 sec\n                    <jats:italic>vs<\/jats:italic>\n                    50\u00a0mL of IA contrast at 5\u00a0mL\/sec over 10 sec. Region-of-interest markers were applied to anatomical regions to measure attenuation (HU) over time. IA and IV contrast protocols achieved adequate aortic opacification (IA, 455 \u00b1 289\n                    <jats:italic>vs<\/jats:italic>\n                    IV, 450 \u00b1 114 HU). The IA contrast aortic attenuation curve reached peak attenuation compared with IV contrast (IA, 8 vs 23 sec; P &lt; .001). Time to peak attenuation was similar between IA and IV contrast in the portal vein (IA, 38\n                    <jats:italic>vs<\/jats:italic>\n                    IV, 42 sec,\n                    <jats:italic>P<\/jats:italic>\n                    = .25). IA administration achieved a superior contrast-to-noise ratio (CNR) in less time compared with IV (R\n                    <jats:sup>2<\/jats:sup>\n                    = .94;\n                    <jats:italic>P<\/jats:italic>\n                    &lt; .001). IA contrast achieved adequate opacification with less bolus broadening and a superior CNR compared with IV contrast while using a smaller contrast volume for directed organ-directed imaging.\n                  <\/jats:p>","DOI":"10.1177\/00033197231155225","type":"journal-article","created":{"date-parts":[[2023,2,8]],"date-time":"2023-02-08T15:44:15Z","timestamp":1675871055000},"page":"833-840","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Exploring Intra-arterial Contrast Administration for Intraoperative Imaging Using a Swine Model"],"prefix":"10.1177","volume":"76","author":[{"given":"Rebecca N.","family":"Treffalls","sequence":"first","affiliation":[{"name":"R. Adams Cowley Shock Trauma Center, University of Maryland, Baltimore, MD, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kelly","family":"Poe","sequence":"additional","affiliation":[{"name":"School of Medicine, University of Maryland, Baltimore, MD, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hossam","family":"Abdou","sequence":"additional","affiliation":[{"name":"R. Adams Cowley Shock Trauma Center, University of Maryland, Baltimore, MD, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David P.","family":"Stonko","sequence":"additional","affiliation":[{"name":"R. Adams Cowley Shock Trauma Center, University of Maryland, Baltimore, MD, USA"},{"name":"Department of Surgery, The Johns Hopkins Hospital, Baltimore, MD, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Edwards","sequence":"additional","affiliation":[{"name":"R. Adams Cowley Shock Trauma Center, University of Maryland, Baltimore, MD, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Randall R.","family":"DeMartino","sequence":"additional","affiliation":[{"name":"Division of Vascular and Endovascular Surgery, Department of Surgery, Mayo Clinic, Rochester, MN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Ptak","sequence":"additional","affiliation":[{"name":"R. Adams Cowley Shock Trauma Center, University of Maryland, Baltimore, MD, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7462-8456","authenticated-orcid":false,"given":"Jonathan J.","family":"Morrison","sequence":"additional","affiliation":[{"name":"Division of Vascular and Endovascular Surgery, Department of Surgery, Mayo Clinic, Rochester, MN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,2,8]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A1438"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehq302"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2007.08.009"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2362040468"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmp.2020.11.006"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/1754-9485.12790"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/mp.15221"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/TA.0000000000003189"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.3171\/2010.6.JNS10117"},{"key":"e_1_3_3_11_2","first-page":"488","article-title":"Preoperative versus intraoperative image-guided localization of multiple ipsilateral lung nodules","volume":"57","author":"Chao YK","year":"2020","unstructured":"Chao YK, Fang HY, Pan KT, Wen CT, Hsieh MJ. Preoperative versus intraoperative image-guided localization of multiple ipsilateral lung nodules. Eur J Cardio Thorac Surg. 2020;57:488-95.","journal-title":"Eur J Cardio Thorac Surg"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2018.06.088"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.10090908"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0221375"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.3000411"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2013.03.027"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/PEC.0b013e3181b5b8ce"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10140-020-01751-y"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1177\/1708538117690662"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2009.08.010"},{"key":"e_1_3_3_21_2","first-page":"553","article-title":"Contrast media-induced nephropathy in patients undergoing angiography prior to or during vascular surgery: a systematic review","volume":"66","author":"Zaraca F","year":"2011","unstructured":"Zaraca F, Wiedermann CJ, Ebner H. Contrast media-induced nephropathy in patients undergoing angiography prior to or during vascular surgery: a systematic review. Minerva Chir. 2011;66:553-60.","journal-title":"Minerva Chir"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1177\/15266028221118510"}],"container-title":["Angiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00033197231155225","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/00033197231155225","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00033197231155225","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T10:21:07Z","timestamp":1777371667000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/00033197231155225"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,8]]},"references-count":21,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["10.1177\/00033197231155225"],"URL":"https:\/\/doi.org\/10.1177\/00033197231155225","relation":{},"ISSN":["0003-3197","1940-1574"],"issn-type":[{"value":"0003-3197","type":"print"},{"value":"1940-1574","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,2,8]]}}}