{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T10:57:25Z","timestamp":1782471445647,"version":"3.54.5"},"reference-count":30,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[2023,6,26]],"date-time":"2023-06-26T00:00:00Z","timestamp":1687737600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100016036","name":"Health\u223cHolland, PPP Allowance Top Sector Life Sciences & Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016036","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010668","name":"H2020 Leadership in Enabling and Industrial Technologies","doi-asserted-by":"publisher","award":["871908"],"award-info":[{"award-number":["871908"]}],"id":[{"id":"10.13039\/100010668","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Angiology"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:p>Contemporary quality control methods are often insufficient in predicting clinical outcomes after revascularization in lower extremity arterial disease (LEAD) patients. This study evaluates the potential of near-infrared fluorescence imaging with indocyanine green to predict the clinical outcome following revascularization. Near-infrared fluorescence imaging was performed before and within 5\u00a0days following the revascularization procedure. Clinical improvement was defined as substantial improvement of pain free walking distance, reduction of rest- and\/or nocturnal pain, or tendency toward wound healing. Time-intensity curves and 8 perfusion parameters were extracted from the dorsum of the treated foot. The quantified postinterventional perfusion improvement was compared within the clinical outcome groups. Successful near-infrared fluorescence imaging was performed in 72 patients (76 limbs, 52.6% claudication, 47.4% chronic limb-threatening ischemia) including 40 endovascular- and 36 surgical\/hybrid revascularizations. Clinical improvement was observed in 61 patients. All perfusion parameters showed a significant postinterventional difference in the clinical improvement group ( P-values &lt;.001), while no significant differences were seen in the group without clinical improvement ( P-values .168\u2013.929). Four parameters demonstrated significant differences in percentage improvement comparing the outcome groups ( P-values within .002\u2013.006). Near-infrared fluorescence imaging has promising additional value besides clinical parameters for predicting the clinical outcome of revascularized LEAD patients.<\/jats:p>","DOI":"10.1177\/00033197231186096","type":"journal-article","created":{"date-parts":[[2023,6,26]],"date-time":"2023-06-26T09:44:39Z","timestamp":1687772679000},"page":"884-892","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":21,"title":["Near-Infrared Fluorescence Imaging With Indocyanine Green to Predict Clinical Outcome After Revascularization in Lower Extremity Arterial Disease"],"prefix":"10.1177","volume":"75","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7274-2802","authenticated-orcid":false,"given":"Floris P.","family":"Tange","sequence":"first","affiliation":[{"name":"Department of Surgery, Leiden University Medical Center, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pim","family":"van den Hoven","sequence":"additional","affiliation":[{"name":"Department of Surgery, Leiden University Medical Center, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"van Schaik","sequence":"additional","affiliation":[{"name":"Department of Surgery, Leiden University Medical Center, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abbey","family":"Schepers","sequence":"additional","affiliation":[{"name":"Department of Surgery, Leiden University Medical Center, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koen E.A.","family":"van der Bogt","sequence":"additional","affiliation":[{"name":"Department of Surgery, Leiden University Medical Center, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catharina S. 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