{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T15:58:04Z","timestamp":1785427084209,"version":"3.56.0"},"reference-count":51,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2023,9,9]],"date-time":"2023-09-09T00:00:00Z","timestamp":1694217600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2019\/23496-8"],"award-info":[{"award-number":["2019\/23496-8"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Angiology"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:p>Increased arterial stiffness is independently associated with cardiovascular risk. Obstructive sleep apnea (OSA) and sleep duration (SDUR) may contribute to increased arterial stiffness, but it is unclear whether this association is modulated by gender. We aimed to evaluate the potential impact of gender in modulating the association of OSA and SDUR with arterial stiffness. Participants from the ELSA-Brasil study performed sleep assessments with portable polygraph to define OSA severity and SDUR by 1-week wrist actigraphy. Pulse wave velocity (PWV) was measured using a standard technique without access to the sleep data. We studied 1863 participants (42.2% male, age: 49\u00b18 years, respiratory disturbance index (RDI): 9.9 (4.5\u201319.4) events\/h, SDUR: 6.5 (5.9\u20137.1) hours, mean PWV: 7.3 \u00b1 1.2 m\/s). We found that men had higher PWV, higher frequency of diabetes, and higher blood pressure when compared to women. The regression analysis showed an independent association between increased RDI and PWV in men (\u00df: 0.007; 95% CI: 0.001\u20130.012), but not in women. In contrast, an independent association between SDUR and increased arterial stiffness was observed only in women (\u00df: 0.068; 95% CI: 0.002\u20130.134). In conclusion, the association of sleep disorders with arterial stiffness showed a distinct gender pattern depending on the sleep variable studied.<\/jats:p>","DOI":"10.1177\/00033197231193618","type":"journal-article","created":{"date-parts":[[2023,9,9]],"date-time":"2023-09-09T06:03:44Z","timestamp":1694239424000},"page":"976-984","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Gender Modulated the Association of Sleep Apnea and Sleep Duration with Arterial Stiffness: The ELSA-Brasil Study"],"prefix":"10.1177","volume":"75","author":[{"given":"Lorenna F.","family":"Cunha","sequence":"first","affiliation":[{"name":"Center of Clinical and Epidemiologic Research (CPCE), University of Sao Paulo, Sao Paulo, Brazil"},{"name":"Unidade de Hipertens\u00e3o, Disciplina de Nefrologia, Hospital das Cl\u00ednicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, 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