{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T18:37:28Z","timestamp":1777401448448,"version":"3.51.4"},"reference-count":34,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2024,2,6]],"date-time":"2024-02-06T00:00:00Z","timestamp":1707177600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Angiology"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:p>Peripheral arterial disease (PAD) studies in rural populations are limited. The incidence of myocardial infarction (MI) is higher in patients with PAD. This study examined the association between sociodemographic and clinical risk factors and MI in patients with PAD in Central Appalachia, comprising of 230 counties across six states in the United States. Data from electronic medical records of 13,455 patients with PAD were extracted from a large health system in Central Appalachia. Bivariate and logistic regression analyses were conducted. The final sample consisted of 5574 patients with PAD, of whom 24.85% were also diagnosed with MI. The mean age was 71 \u00b1 11.23\u00a0years, and the majority were male (56.40%). After adjusting for confounders, patients with hypertension had three times higher odds of MI (adjusted Odds Ratio [aOR] = 3.21; 95% CI: 2.50\u20134.14) compared with those without hypertension. The likelihood of MI increased by 51% among patients with diabetes (aOR = 1.51; 95% CI: 1.33\u20131.71), 34% among ever-smokers (aOR = 1.34; 95% CI: 1.18\u20131.52), and 45% in males (aOR = 1.45; 95% CI: 1.27\u20131.65). Hypertension, diabetes, smoking, and male sex were identified as significant risk factors for MI. Screening and effective management of these risk factors in rural areas could potentially prevent MI incidence among patients with PAD.<\/jats:p>","DOI":"10.1177\/00033197241232608","type":"journal-article","created":{"date-parts":[[2024,2,6]],"date-time":"2024-02-06T12:39:07Z","timestamp":1707223147000},"page":"674-680","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Factors Associated With Myocardial Infarction in a Rural Population With Peripheral Arterial Diseases"],"prefix":"10.1177","volume":"76","author":[{"given":"Adeola O.","family":"Awujoola","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Bronxcare Health System, Bronx, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7234-0624","authenticated-orcid":false,"given":"Moboni T.","family":"Mokikan","sequence":"additional","affiliation":[{"name":"Life Health Center, Wilmington, DE, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9734-4170","authenticated-orcid":false,"given":"Olufeyisayo O.","family":"Odebunmi","sequence":"additional","affiliation":[{"name":"University of North Carolina, Chapel Hill, NC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3304-5577","authenticated-orcid":false,"given":"Hadii M.","family":"Mamudu","sequence":"additional","affiliation":[{"name":"Center for Cardiovascular Risk Research, College of Public Health, East Tennessee State University, Johnson City, TN, USA"},{"name":"Department of Health Services Management and Policy, College of Public Health, East Tennessee State University, Johnson City, TN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David W.","family":"Stewart","sequence":"additional","affiliation":[{"name":"Center for Cardiovascular Risk Research, College of Public Health, East Tennessee State University, Johnson City, TN, USA"},{"name":"Bill Gatton College of Pharmacy, East Tennessee State University, Johnson City, TN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ghaith","family":"Husari","sequence":"additional","affiliation":[{"name":"Center for Cardiovascular Risk Research, College of Public Health, East Tennessee State University, Johnson City, TN, USA"},{"name":"Department of Computer Science, East Tennessee State University, Johnson City, TN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krishna","family":"Singh","sequence":"additional","affiliation":[{"name":"Center for Cardiovascular Risk Research, College of Public Health, East Tennessee State University, Johnson City, TN, USA"},{"name":"Department of Biomedical Sciences, James H. 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Health disparities in Appalachia: the first report in a series exploring health issues in Appalachia. https:\/\/www.arc.gov\/assets\/research_reports\/Health_Disparities_in_Appalachia_August_2017.pdf (2017, accessed 29 September 2018)."},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000137913.26087.F0"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2019.09.012"},{"key":"e_1_3_4_10_2","first-page":"CR131","article-title":"Incidence of new cardiovascular events in patients with and without peripheral arterial disease seen in a vascular surgery clinic","volume":"18","author":"Chhabra A","year":"2012","unstructured":"Chhabra A, Aronow WS, Ahn C, et al. Incidence of new cardiovascular events in patients with and without peripheral arterial disease seen in a vascular surgery clinic. 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Rural Appalachia compared to the rest of rural America. https:\/\/www.arc.gov\/about-the-appalachian-region\/the-chartbook\/rural-appalachia\/ (accessed 13 October 2023)."},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1136\/openhrt-2018-001004"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1159\/000497790"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.semvascsurg.2022.05.003"},{"key":"e_1_3_4_16_2","volume-title":"No leading health indicators title","author":"U.S. Department of Health and Human Services","unstructured":"U.S. Department of Health and Human Services. 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