{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T18:37:25Z","timestamp":1777401445963,"version":"3.51.4"},"reference-count":25,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2024,2,11]],"date-time":"2024-02-11T00:00:00Z","timestamp":1707609600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Angiology"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:p>\n                    The present study evaluated the prognostic significance of right ventricular-pulmonary arterial (RV-PA) coupling, assessed by the tricuspid annular plane systolic excursion to systolic pulmonary artery pressure (TAPSE\/sPAP) ratio, in patients undergoing transcatheter aortic valve implantation (TAVI) for severe aortic stenosis (AS). This retrospective, single-center study involved 403 patients (mean age: 78.2 \u00b1 8.4; 50.9% female). RV-PA coupling was categorized based on the pre-procedural TAPSE\/sPAP ratio: severe uncoupling (\u22640.32), moderate uncoupling (0.32\u20130.55), and normal coupling (&gt;0.55). The study primary endpoints were in-hospital mortality and 2-year all-cause mortality. Multivariate logistic regression revealed that the TAPSE\/sPAP ratio is an independent predictor of both in-hospital (adjusted OR: 0.61, 95% CI [0.44\u20130.84],\n                    <jats:italic>P<\/jats:italic>\n                    = .002) and 2-year mortality (adjusted OR: 0.69, 95% CI [0.56\u20130.85],\n                    <jats:italic>P<\/jats:italic>\n                    = .001). Severe uncoupling was strongly associated with increased 2-year mortality (adjusted OR: 3.92, 95% CI [1.67\u20139.20],\n                    <jats:italic>P<\/jats:italic>\n                    = .002). Our study establishes a significant association between reduced preoperative TAPSE\/sPAP ratios and increased risks of both in-hospital and 2-year all-cause mortality in patients undergoing TAVI for severe AS. These results highlight the prognostic utility of evaluating RV-PA coupling. Incorporating this metric into preoperative risk stratification could potentially refine prognostic accuracy and inform clinical decision-making.\n                  <\/jats:p>","DOI":"10.1177\/00033197241232723","type":"journal-article","created":{"date-parts":[[2024,2,11]],"date-time":"2024-02-11T23:25:55Z","timestamp":1707693955000},"page":"340-348","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["The Influence of Preoperative Right Ventricle to Pulmonary Arterial Coupling on Short- and Long-Term Prognosis in Patients Who Underwent Transcatheter Aortic Valve Implantation"],"prefix":"10.1177","volume":"76","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8252-0373","authenticated-orcid":false,"given":"Aykun","family":"Hakgor","sequence":"first","affiliation":[{"name":"Medipol Mega University Hospital, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Basak Catalbas","family":"Kahraman","sequence":"additional","affiliation":[{"name":"Medipol Mega University Hospital, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atakan","family":"Dursun","sequence":"additional","affiliation":[{"name":"Medipol Mega University Hospital, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arzu","family":"Yazar","sequence":"additional","affiliation":[{"name":"Medipol Mega University Hospital, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Umeyir","family":"Savur","sequence":"additional","affiliation":[{"name":"Medipol Mega University Hospital, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aysel","family":"Akhundova","sequence":"additional","affiliation":[{"name":"Medipol Mega University Hospital, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatih Erkam","family":"Olgun","sequence":"additional","affiliation":[{"name":"Medipol Mega University Hospital, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melike Zeynep","family":"Kenger","sequence":"additional","affiliation":[{"name":"Medipol Mega University Hospital, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bilal","family":"Boztosun","sequence":"additional","affiliation":[{"name":"Medipol Mega University Hospital, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,2,11]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2021.2133"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehab395"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.117.005481"},{"issue":"0","key":"e_1_3_4_5_2","first-page":"33197231177397","article-title":"Evaluation of hematological parameters after transcatheter aortic valve replacement","volume":"0","author":"Karahan MZ","year":"2023","unstructured":"Karahan MZ, Aktan A, G\u00fczel T, et al. Evaluation of hematological parameters after transcatheter aortic valve replacement. Angiology. 2023;0(0):33197231177397.","journal-title":"Angiology"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2022.08.757"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.carrev.2018.03.015"},{"key":"e_1_3_4_8_2","first-page":"150","article-title":"Right ventricular deformation and right ventricular-arterial coupling in patients with heart failure due to severe aortic stenosis undergoing TAVI: long-term results","volume":"10","author":"Vizzardi E","year":"2020","unstructured":"Vizzardi E, Gavazzoni M, Sciatti E, et al. Right ventricular deformation and right ventricular-arterial coupling in patients with heart failure due to severe aortic stenosis undergoing TAVI: long-term results. 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Validation of the tricuspid annular plane systolic excursion\/systolic pulmonary artery pressure ratio for the assessment of right ventricular-arterial coupling in severe pulmonary hypertension. 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