{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T23:46:13Z","timestamp":1790811973229,"version":"4.1.0"},"reference-count":41,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2024,8,12]],"date-time":"2024-08-12T00:00:00Z","timestamp":1723420800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Angiology"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:p>\n                    Frozen elephant trunk (FET) has gained popularity since its inception. Nevertheless, the optimal approach for managing aortic arch pathologies remains subject of debate. This meta-analysis compared outcomes between patients undergoing FET and those undergoing conventional aortic repair. Systematic searches were conducted up to February 2024. Pooled results of short and long-term outcomes were computed. A systematic review identified 21 non-randomized studies encompassing 3240 patients. Short-term mortality was lower in FET recipients than in those undergoing conventional repair (OR [95% CI] = 0.58 [0.44\u20130.78],\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    &lt; .01). Postoperative paraplegia incidence was higher in the FET cohort (OR = 1.85 [1.02\u20133.34],\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    = .04), while subgroup analysis showed no difference between the two groups in patients with acute aortic dissection. Long-term all-cause mortality was lower among FET recipients. Subgroup analysis showed FET was associated with reduced all-cause mortality (HR = 0.55 [0.39\u20130.79],\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    &lt; .01) and aortic re-intervention (HR = 0.62 [0.39\u20130.99],\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    = .05) in acute aortic dissection patients. This meta-analysis underscores the favorable association between the utilization of FET and improved short and long-term outcomes compared with conventional repair, while paraplegia incidence was higher in the FET group. FET appears to offer superior benefits, particularly evident in patients with acute aortic dissection.\n                  <\/jats:p>","DOI":"10.1177\/00033197241273421","type":"journal-article","created":{"date-parts":[[2024,8,12]],"date-time":"2024-08-12T15:49:06Z","timestamp":1723477746000},"page":"161-175","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Systematic Review and Meta-Analysis With Reconstructed Time-To-Event Data of Frozen Elephant Trunk and Conventional Aortic Repair"],"prefix":"10.1177","volume":"77","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1789-5993","authenticated-orcid":false,"given":"Noritsugu","family":"Naito","sequence":"first","affiliation":[{"name":"Shizuoka Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5594-8072","authenticated-orcid":false,"given":"Hisato","family":"Takagi","sequence":"additional","affiliation":[{"name":"Shizuoka Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,8,12]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2015.05.029"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezab192"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1020290"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(03)00045-X"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/jocs.15452"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/jocs.15730"},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.1067\/mtc.2002.122302"},{"key":"e_1_3_5_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12055-021-01302-1"},{"key":"e_1_3_5_10_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.semtcvs.2021.03.049"},{"key":"e_1_3_5_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezz104"},{"key":"e_1_3_5_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2019.10.031"},{"key":"e_1_3_5_13_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71"},{"key":"e_1_3_5_14_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2288-12-9"},{"key":"e_1_3_5_15_2","doi-asserted-by":"publisher","DOI":"10.1177\/1536867X1801700402"},{"key":"e_1_3_5_16_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12874-021-01308-8"},{"key":"e_1_3_5_17_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.315.7109.629"},{"key":"e_1_3_5_18_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.i4919"},{"key":"e_1_3_5_19_2","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezad122"},{"key":"e_1_3_5_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.avsg.2023.05.001"},{"key":"e_1_3_5_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2021.03.079"},{"key":"e_1_3_5_22_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00595-021-02337-y"},{"key":"e_1_3_5_23_2","doi-asserted-by":"publisher","DOI":"10.1093\/icvts\/ivaa199"},{"key":"e_1_3_5_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2018.11.145"},{"key":"e_1_3_5_25_2","doi-asserted-by":"publisher","DOI":"10.1093\/icvts\/ivz154"},{"key":"e_1_3_5_26_2","doi-asserted-by":"publisher","DOI":"10.21037\/jtd.2018.10.42"},{"key":"e_1_3_5_27_2","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezx199"},{"key":"e_1_3_5_28_2","first-page":"754","article-title":"Modified frozen elephant trunk for acute type A aortic dissection: a comparative study with standard repair technique","volume":"51","author":"Matt P","year":"2017","unstructured":"Matt P, Banerjee P, Grapow M, et al. 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