{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T17:12:11Z","timestamp":1787073131147,"version":"build-2736575974"},"reference-count":40,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T00:00:00Z","timestamp":1760918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Angiology"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:p>\n                    The CHA\n                    <jats:sub>2<\/jats:sub>\n                    DS\n                    <jats:sub>2<\/jats:sub>\n                    -VASc score includes classical risk factors (e.g., Congestive heart failure\/Left ventricle dysfunction, Hypertension, Age, Diabetes mellitus, Stroke\/Transient ischemic attack\/Thromboembolism, Vascular disease and Sex) for coronary artery disease. We investigated the association between initial thrombolysis in myocardial infarction (TIMI) flow of the culprit artery and CHA\n                    <jats:sub>2<\/jats:sub>\n                    DS\n                    <jats:sub>2<\/jats:sub>\n                    -VASc score and in-hospital clinical outcomes in patients presenting with acute myocardial infarction (AMI). Initial and postprocedural TIMI flow grades were recorded in patients hospitalized with first diagnosis of AMI. The initial TIMI flow grades and CHA\n                    <jats:sub>2<\/jats:sub>\n                    DS\n                    <jats:sub>2<\/jats:sub>\n                    VASC scores were compared with the post-procedural TIMI flow grades. Patients (n\u2009=\u2009750) were included retrospectively; 56.7% was in the low flow (TIMI 0-1) and 43.3% was in the high flow (TIMI 2-3) group. The CHA\n                    <jats:sub>2<\/jats:sub>\n                    DS\n                    <jats:sub>2<\/jats:sub>\n                    -VASc score was higher (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009&lt;\u2009.001) in the low flow group. The best CHA\n                    <jats:sub>2<\/jats:sub>\n                    DS\n                    <jats:sub>2<\/jats:sub>\n                    -VASc score cut-off value was 3 to predict initial TIMI flow. Median CHA\n                    <jats:sub>2<\/jats:sub>\n                    DS\n                    <jats:sub>2<\/jats:sub>\n                    -VASc score was 4 in-hospital mortality group (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009&lt;\u2009.001) and this score was an independent predictor of in-hospital mortality. The CHA\n                    <jats:sub>2<\/jats:sub>\n                    DS\n                    <jats:sub>2<\/jats:sub>\n                    -VASc score was an independent predictor of low initial TIMI flow and in-hospital mortality. Patients with high preprocedural CHA\n                    <jats:sub>2<\/jats:sub>\n                    DS\n                    <jats:sub>2<\/jats:sub>\n                    -VASc tended to have low coronary flow grades and higher mortality rates.\n                  <\/jats:p>","DOI":"10.1177\/00033197251378891","type":"journal-article","created":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T06:14:35Z","timestamp":1761027275000},"page":"1036-1043","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["The Relation Between CHA2DS2-VASc Score, Initial TIMI Flow Grades and In-Hospital Mortality in Patients Presenting with Acute Myocardial Infarction"],"prefix":"10.1177","volume":"77","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6827-7132","authenticated-orcid":false,"given":"Funda Ozlem","family":"Pamuk","sequence":"first","affiliation":[{"name":"Department of Cardiology, Ankara Bilkent City Hospital, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1470-547X","authenticated-orcid":false,"given":"Hatice Mediha","family":"K\u0131na","sequence":"additional","affiliation":[{"name":"Department of Neurology, Ankara Education and Research Hospital, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4484-4259","authenticated-orcid":false,"given":"Esra","family":"D\u00f6nmez","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Bagcilar Training and Research Hospital, \u0130stanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ceren Ya\u011fmur","family":"Do\u011fru","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Ankara Bilkent City Hospital, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hatice","family":"Sel\u00e7uk","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Ankara Bilkent City Hospital, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,10,20]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.04.052"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcad.2007.11.003"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198510173131611"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11239-013-0977-x"},{"issue":"11","key":"e_1_3_2_6_2","first-page":"1782","article-title":"Relationship between residual blood flow in the infarct-related artery and scintigraphic infarct size, myocardial salvage, and functional recovery in patients with acute myocardial infarction","volume":"46","author":"Ndrepepa G","year":"2005","unstructured":"Ndrepepa G, Kastrati A, Schwaiger M, et al Relationship between residual blood flow in the infarct-related artery and scintigraphic infarct size, myocardial salvage, and functional recovery in patients with acute myocardial infarction. 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