{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T22:34:45Z","timestamp":1785191685251,"version":"3.55.0"},"reference-count":53,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T00:00:00Z","timestamp":1761868800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Angiology"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:p>\n                    The present study evaluated the changes in retinal vascular structure among patients with retinal vein occlusion (RVO) according to varying cardiovascular risk (CVR) scores. We analyzed clinical data, blood tests, ophthalmic exams, and macular vascular parameters measured with optical coherence tomography angiography (OCTA) and CVR scores. This study included 21 patients with central retinal vein occlusion (CRVO), 35 patients with branch retinal vein occlusion (BRVO), and 60 control subjects with refractive disorders and no other abnormalities. In eyes with RVO, macular vascular densities in the superficial capillary plexus were significantly lower in all quadrants compared with controls (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009&lt;\u2009.05), while in the deep capillary plexus, significant reductions were observed in all quadrants except the nasal quadrant (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009&lt;\u2009.05). Both superficial and deep foveal avascular zone (FAZ) areas were significantly larger in RVO eyes compared with the control group (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009&lt;\u2009.001 for all). CVR scores were significantly higher in RVO patients compared with the control group (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009&lt;\u2009.001 for all). CVR scores were highest in CRVO patients (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009&lt;\u2009.001). Deep FAZ areas showed positive correlations with CVR scores. The present findings suggest that cardiovascular disease risk should be assessed in patients with RVO.\n                  <\/jats:p>","DOI":"10.1177\/00033197251379119","type":"journal-article","created":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T11:01:36Z","timestamp":1761908496000},"page":"693-703","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Evaluation of Cardiovascular Risk Scores and their Association With Vascular Structural Changes in Patients With Retinal Vein Occlusion"],"prefix":"10.1177","volume":"77","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1694-6864","authenticated-orcid":false,"given":"Ulviye","family":"K\u0131vrak","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, University of Health Sciences, Kartal L\u00fctfi K\u0131rdar City Hospital, Istanbul, T\u00fcrkiye"},{"name":"Advanced Neurological Sciences, Istanbul University Institute of Graduate Studies in Health Sciences, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0737-6927","authenticated-orcid":false,"given":"Tuba","family":"Unkun","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Kartal Kosuyolu Heart Education and Research Hospital, Istanbul, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,10,31]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp1003934"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2009.07.017"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.17116\/oftalma2015131651-56"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1080\/14779072.2022.2112667"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/aos.14141"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1080\/09286586.2024.2321902"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/eye.2000.230"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2016.02.024"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.97.18.1837"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.0000437741.48606.98"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.5543\/tkda.2023.74249"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcjo.2012.08.017"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.86.7.774"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2014.3616"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1986.01050130044017"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1997.01100150488006"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1985.01050120030015"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehab309"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehad260"},{"key":"e_1_3_2_21_2","article-title":"Monitoring health for the SDGs, sustainable development goals","author":"World Health Statistics","year":"2023","unstructured":"World Health Statistics. Monitoring health for the SDGs, sustainable development goals. WHO; 2023.","journal-title":"WHO;"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2006.06.061"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2007.01.031"},{"key":"e_1_3_2_24_2","article-title":"British Cardiac Society, British Hyperlipidaemia Association, British Hypertension Society, endorsed by the British Diabetic Association","volume":"80","author":"Joint British recommendations on prevention of coronary heart disease in clinical practice","year":"1998","unstructured":"Joint British recommendations on prevention of coronary heart disease in clinical practice. British Cardiac Society, British Hyperlipidaemia Association, British Hypertension Society, endorsed by the British Diabetic Association. Heart. 1998;80(suppl 2):S1-S29.","journal-title":"Heart"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10792-021-02015-5"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.16-21208"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pdpdt.2022.103244"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2018.3586"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2017.02.015"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.121.10.1488"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm13030829"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10792-022-02361-y"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1097\/iae.0000000000000845"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.4103\/joco.joco_163_21"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1159\/000445482"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1167\/iovs-16-20648"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.4103\/jovr.jovr_264_17"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.1038\/srep40763"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0176404"},{"key":"e_1_3_2_40_2","doi-asserted-by":"publisher","DOI":"10.7417\/ct.2020.2269"},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.1097\/md.0000000000028424"},{"key":"e_1_3_2_42_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2022-321225"},{"key":"e_1_3_2_43_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2013.07.025"},{"key":"e_1_3_2_44_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0184016"},{"key":"e_1_3_2_45_2","first-page":"545","article-title":"The eye disease case-control study group","volume":"114","author":"Risk factors for central retinal vein occlusion","year":"1996","unstructured":"Risk factors for central retinal vein occlusion. The eye disease case-control study group. Arch Ophthalmol. 1996;114:545-554","journal-title":"Arch Ophthalmol"},{"key":"e_1_3_2_46_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mvr.2019.103908"},{"key":"e_1_3_2_47_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2006.090522"},{"key":"e_1_3_2_48_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0039-6257(01)00234-x"},{"key":"e_1_3_2_49_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2018.07.022"},{"key":"e_1_3_2_50_2","doi-asserted-by":"publisher","DOI":"10.4103\/jovr.jovr_173_17"},{"key":"e_1_3_2_51_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hlc.2013.03.083"},{"key":"e_1_3_2_52_2","doi-asserted-by":"publisher","DOI":"10.1111\/aos.12594"},{"key":"e_1_3_2_53_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ihj.2017.01.015"},{"key":"e_1_3_2_54_2","doi-asserted-by":"publisher","DOI":"10.18502\/ijph.v52i2.11895"}],"container-title":["Angiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00033197251379119","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/00033197251379119","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00033197251379119","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T10:21:42Z","timestamp":1779358902000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/00033197251379119"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,31]]},"references-count":53,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.1177\/00033197251379119"],"URL":"https:\/\/doi.org\/10.1177\/00033197251379119","relation":{},"ISSN":["0003-3197","1940-1574"],"issn-type":[{"value":"0003-3197","type":"print"},{"value":"1940-1574","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,31]]}}}