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It could be potentially life-threatening if left untreated due to its catastrophic rupture. The pooled incidence and prevalence of TAAs is about 5.3 per 100\u2009000 individuals\/year and 0.16%, respectively. The pooled incidence of ruptured aneurysms was estimated at 1.6 per 100\u2009000 individuals\/year. Genetic studies indicate that the somatic\n                    <jats:italic toggle=\"yes\">JAK2<\/jats:italic>\n                    <jats:sup>V617F<\/jats:sup>\n                    sequence variation is strongly and independently linked with TAAs. Investigators have suggested that irrespective of the absolute aortic diameter values, patients with an aortic height index (AHI) exceeding 2.9\u2009cm\/m should be referred to an aortic center for multidisciplinary risk assessment. All the issues concerning ascending aorta aneurysm are herein detailed; the results of meta-analyses of relevant studies are discussed and tabulated and the types of aneurysms and diseases of the ascending aorta and the surgical repair techniques of these pathologies are described and pictorially illustrated.\n                  <\/jats:p>","DOI":"10.1177\/00033197261428508","type":"journal-article","created":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T10:30:41Z","timestamp":1775039441000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Ascending Aorta Aneurysm: What the Cardiologist Needs to Know"],"prefix":"10.1177","author":[{"given":"Antonis A.","family":"Manolis","sequence":"first","affiliation":[{"name":"Department of Medicine, Elpis General Hospital, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theodora A.","family":"Manolis","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Aiginiteio University Hospital, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Apostolos","family":"Vouliotis","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Euroclinic Hospital, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0336-4745","authenticated-orcid":false,"given":"Antonis S.","family":"Manolis","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Hippokrateio University Hospital, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,4,1]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2021.06.016"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.semtcvs.2021.02.029"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2025.06.019"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.125.074002"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehae179"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2018.1281"},{"key":"e_1_3_2_8_2","first-page":"9590","article-title":"Ascending aorta replacement vs. total aortic arch replacement in the treatment of acute type A dissection: a meta-analysis","volume":"23","author":"Hsieh WC","year":"2019","unstructured":"Hsieh WC, Kan CD, Yu HC, et al. 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