{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T15:30:14Z","timestamp":1791473414323,"version":"4.3.4"},"reference-count":31,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T00:00:00Z","timestamp":1786406400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Angiology"],"abstract":"<jats:p>\n                    Older adults face a high risk of in-hospital mortality following acute coronary syndrome (ACS). The C-reactive protein-albumin-lymphocyte (CALLY) index reflects systemic inflammation, immunity, and nutritional status. We investigated its predictive value for in-hospital mortality in elderly ACS patients. A total of 699 older patients diagnosed with ACS were retrospectively analyzed. The cohort was divided into survivors (n\u2009=\u2009562) and non-survivors (n\u2009=\u2009137). Admission values of serum C-reactive protein, albumin, and lymphocyte counts were utilized to compute the CALLY index. The non-survivor cohort exhibited a remarkably lower CALLY index compared with those who survived (0.22 [0.08-0.78] vs 3.09 [0.73-10.3],\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009&lt;\u2009.001). A CALLY index threshold of \u22640.716 identified in-hospital mortality with 75.4% sensitivity and 74.5% specificity (Area under the curve [AUC]\u2009=\u20090.816, 95% CI: 0.776-0.856,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009&lt;\u2009.001), showing higher sensitivity and specificity than the Global Registry of Acute Coronary Events (GRACE) score. Multivariable regression revealed that CALLY index &lt;0.716 (odds ratio [OR]\u2009=\u20094.41, 95% CI: 2.27-8.54,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009&lt;\u2009.001) independently predicted adverse outcomes. The CALLY index may serve as a valuable and independent prognostic marker in elderly patients with ACS.\n                  <\/jats:p>","DOI":"10.1177\/00033197261476789","type":"journal-article","created":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T04:50:02Z","timestamp":1786510202000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Association of the C-Reactive Protein-Albumin-Lymphocyte (CALLY) Index With In-Hospital Mortality Among Elderly Patients Admitted for Acute Coronary Syndrome"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5126-0959","authenticated-orcid":false,"given":"Oguz","family":"Kilic","sequence":"first","affiliation":[{"name":"Department of Cardiology, Karaman Research and Training Hospital, Karamanoglu Mehmetbey University, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8047-389X","authenticated-orcid":false,"given":"Damla","family":"Yalcinkaya Oner","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Karaman Training and Research Hospital, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2154-1581","authenticated-orcid":false,"given":"Kadir","family":"Karacali","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Golbasi Sehit Ahmet Ozsoy State Hospital, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6530-9728","authenticated-orcid":false,"given":"Mehmet","family":"Mustu","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Karaman Research and Training Hospital, Karamanoglu Mehmetbey University, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-0659-5053","authenticated-orcid":false,"given":"Serdal","family":"Bay","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Karaman Training and Research Hospital, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-6749-7035","authenticated-orcid":false,"given":"Rumeysa Nedret","family":"Basdas","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Karaman Training and Research Hospital, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5839-9104","authenticated-orcid":false,"given":"Fatma Ozpamuk","family":"Karadeniz","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Karaman Research and Training Hospital, Karamanoglu Mehmetbey University, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,8,11]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00380-023-02260-x"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.182615"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.25011\/cim.v41i2.29914"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/ggi.12759"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.3390\/nu16010001"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.00754"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2019.10.031"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2004.06.001"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hpb.2021.06.414"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1177\/03000605261416756"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.5761\/atcs.oa.25-00156"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13019-025-03763-6"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13195018"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2024.e37197"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12933-025-02876-5"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.31623"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2024.112860"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2022.05.004"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1159\/000089437"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1161\/hc0902.104353"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfl037"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiochem.2010.08.025"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2021.03.040"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1177\/1076029613499821"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780350824"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.97.5.425"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2796.2000.00670.x"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1111\/1753-0407.13610"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1007\/s13300-018-0454-9"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehx393"},{"key":"e_1_3_2_32_2","article-title":"Comparison 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Comparison of clinical and angiographic prognostic risk scores in elderly patients presenting with acute coronary syndrome and referred for percutaneous coronary intervention. 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