{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T17:51:47Z","timestamp":1777398707604,"version":"3.51.4"},"reference-count":32,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[1983,9,1]],"date-time":"1983-09-01T00:00:00Z","timestamp":431222400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Angiology"],"published-print":{"date-parts":[[1983,9]]},"abstract":"<jats:p>Thrombolytic therapy was carried out on four patients with brain stem stroke due to thromboembolism of the vertebrobasilar system. Diagnosis was confirmed by angiography. Clinical and instrumental findings indicated a very poor prognosis. Two of these patients were treated with urokinase and the other two with streptokinase for periods ranging from 16 to 44 hours. The interval between onset of symptoms and start of therapy was less than 10 hours for three of these patients. All made a gradual and almost complete recovery after only a few hours of treatment, and only one presented minimal residual neurological disability. The conditionof the fourth patient, who started therapy four days after the first episode, remained unchanged until he died 16 hours later.<\/jats:p>\n                  <jats:p>Our observations suggest that thrombolytic therapy may be useful in treat ing recent acute life-threatening brain stem stroke.<\/jats:p>","DOI":"10.1177\/000331978303400901","type":"journal-article","created":{"date-parts":[[2007,11,26]],"date-time":"2007-11-26T17:46:29Z","timestamp":1196099189000},"page":"561-571","source":"Crossref","is-referenced-by-count":65,"title":["Thrombolytic Therapy for Thromboembolism of Vertebrobasilar Artery"],"prefix":"10.1177","volume":"34","author":[{"given":"G.G.","family":"Nenci","sequence":"first","affiliation":[{"name":"Institute of Semeiotica Medica, University of Perugia Medical School, Perugia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Gresele","sequence":"additional","affiliation":[{"name":"Institute of Semeiotica Medica, University of Perugia Medical School, Perugia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Taramelli","sequence":"additional","affiliation":[{"name":"Clinica Neurologia, University of Perugia Medical School, Perugia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Agnelli","sequence":"additional","affiliation":[{"name":"Clinica Medica, University of Perugia Medical School, Perugia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Signorini","sequence":"additional","affiliation":[{"name":"University of Perugia Medical School, the Neuroradiological Unit, Regional Hospital, Perugia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1983,9,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-93-5-742"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1977.03280020046022"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.9.2.130"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.10.2.117"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(80)90134-8"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1177\/000331976401501003"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1964.03070050039011"},{"key":"atypb8","first-page":"1737","volume":"31","author":"K\u00e4ssmeyer H.","year":"1965","journal-title":"Med Welt"},{"key":"atypb9","first-page":"2588","volume":"43","author":"Bouschery R.","year":"1967","journal-title":"Med Welt"},{"key":"atypb10","first-page":"2357","volume":"111","author":"Belz von GG","year":"1969","journal-title":"M\u00fcnch Med Wschr"},{"key":"atypb11","first-page":"879","volume":"76","author":"Brooks J.","year":"1970","journal-title":"J Lab Clin Med"},{"key":"atypb12","unstructured":"Malinovsky NN, Kozlov VA: Embolism of the cerebral arteries. In: Anticoagulant and Thrombolytic Therapy in Surgery, ed. by Malinovsky NN, Kozlov VA. St. Louis, C.V. Mosby Company, 1979, pp. 239-250."},{"key":"atypb13","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.7.2.135"},{"key":"atypb14","first-page":"259","volume":"32","author":"Larcan A.","year":"1977","journal-title":"Th\u00e9rapie"},{"key":"atypb15","volume-title":"Proceedings of the fifth international congress on thromboembolism","author":"Labauge R."},{"key":"atypb16","unstructured":"Abe T., Kazama M.: Thrombolytic therapy of cerebrovascular occlusive disease. In: Prophylactic Approach to Hypertensive Diseases, ed. by Yamori Y, Lovenberg W, Freis ED. 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