{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T18:03:43Z","timestamp":1777399423065,"version":"3.51.4"},"reference-count":15,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[1987,1,1]],"date-time":"1987-01-01T00:00:00Z","timestamp":536457600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Angiology"],"published-print":{"date-parts":[[1987,1]]},"abstract":"<jats:p>Myocardial ultrastructural changes are described in a twenty-five-year-old female with typical Kearns-Sayre syndrome.<\/jats:p>\n                  <jats:p>The electrocardiogram revealed complete atrioventricular block with an occasional torsades de pointes type of ventricular tachycardia. His bundle recording demonstrated HV block with normal AH interval.<\/jats:p>\n                  <jats:p>An endomyocardial biopsy showed \"ragged-red fibers\" by the modified Gomori trichrome stain, and on electron microscopy there were increased numbers of morphologically abnormal mitochondria: ie, giant mitochondria, a whorled pattern of the cristae, and electron-dense substances, and paracrystalline inclusions in the mitochondria.<\/jats:p>\n                  <jats:p>The patient has been well since pacemaker implanatation, but she may develop a clinically overt cardiomyopathy due to progression of myocardial involvement.<\/jats:p>","DOI":"10.1177\/000331978703800104","type":"journal-article","created":{"date-parts":[[2007,11,26]],"date-time":"2007-11-26T17:46:29Z","timestamp":1196099189000},"page":"28-35","source":"Crossref","is-referenced-by-count":12,"title":["Myocardial Ultrastructure in Kearns-Sayre Syndrome"],"prefix":"10.1177","volume":"38","author":[{"given":"Takeshi","family":"Nakano","sequence":"first","affiliation":[{"name":"First Department of Internal Medicine, Mie University School of Medicine, Tsu, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyoko","family":"Imanaka","sequence":"additional","affiliation":[{"name":"First Department of Internal Medicine, Mie University School of Medicine, Tsu, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideki","family":"Uchida","sequence":"additional","affiliation":[{"name":"First Department of Internal Medicine, Mie University School of Medicine, Tsu, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoki","family":"Isaka","sequence":"additional","affiliation":[{"name":"First Department of Internal Medicine, Mie University School of Medicine, Tsu, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideo","family":"Takezawa","sequence":"additional","affiliation":[{"name":"First Department of Internal Medicine, Mie University School of Medicine, Tsu, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1987,1,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1958.00940080296016"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(67)90015-0"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(67)90016-2"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1972.00490090019001"},{"key":"atypb5","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/0022-510X(73)90158-5","volume":"19","author":"Karpati G.","year":"1973","journal-title":"J Neurol Sciences"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1378\/chest.68.5.727"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1976.03630110054014"},{"key":"atypb8","doi-asserted-by":"crossref","first-page":"1396","DOI":"10.1016\/0002-9149(79)90459-4","volume":"44","author":"Roberts NK","year":"1979","journal-title":"Am J Cardiol"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.35.7.766"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.38.2.117"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.13.11.919"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1968.00470360076008"},{"key":"atypb13","doi-asserted-by":"publisher","DOI":"10.1002\/clc.4960071109"},{"key":"atypb14","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.38.5.526"},{"key":"atypb15","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.63.1.214"}],"container-title":["Angiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000331978703800104","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000331978703800104","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T10:15:02Z","timestamp":1777371302000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/000331978703800104"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1987,1]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1987,1]]}},"alternative-id":["10.1177\/000331978703800104"],"URL":"https:\/\/doi.org\/10.1177\/000331978703800104","relation":{},"ISSN":["0003-3197","1940-1574"],"issn-type":[{"value":"0003-3197","type":"print"},{"value":"1940-1574","type":"electronic"}],"subject":[],"published":{"date-parts":[[1987,1]]}}}