{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T23:43:22Z","timestamp":1784591002204,"version":"3.55.0"},"reference-count":31,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[1988,7,1]],"date-time":"1988-07-01T00:00:00Z","timestamp":583718400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Angiology"],"published-print":{"date-parts":[[1988,7]]},"abstract":"<jats:p>Forty patients, 30 men and 10 women with an average age of 38.47 \u00b1 11.07 years, suffering from ankylosing spondylitis and attending a Rheumatology Outpatient Clinic, were evaluated for cardiovascular involvement. The evaluation was based on patients' clinical observation, electrocardiography, echocardiography, and chest x-ray. More than a simple review, this study was undertaken with the aim of arriving at a better clinical definition of the cardiovascular manifestations found in ankylosing spondylitis. In fact, of the 40 patients, 8 (20%) had systemic hypertension for which an explanation could not be found, 4 of whom were less than forty-five years old; the echocardiogram showed mitral valve prolapse in 4 patients (10%), 2 of them with a systolic murmur and other 2 with a protosystolic click on auscultation. More significant than the changes in conduction was the finding of a sinus bradycardia in 9 patients (22.5%), and a PR interval below 120 msec in 3 patients (7.5%). The authors conclude that the extension of cardiovascular changes in ankylosing spondylitis is more vast than usually acknowledged.<\/jats:p>","DOI":"10.1177\/000331978803900702","type":"journal-article","created":{"date-parts":[[2007,11,26]],"date-time":"2007-11-26T17:46:29Z","timestamp":1196099189000},"page":"567-571","source":"Crossref","is-referenced-by-count":20,"title":["Cardiac Alterations in Ankylosing Spondylitis"],"prefix":"10.1177","volume":"39","author":[{"given":"Mario G.","family":"Alves","sequence":"first","affiliation":[{"name":"Department of Cardiology and Section of Rheumatology, Sta. Maria University Hospital, Lisbon, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge","family":"Espirito-Santo","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Section of Rheumatology, Sta. Maria University Hospital, Lisbon, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario V.","family":"Queiroz","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Section of Rheumatology, Sta. Maria University Hospital, Lisbon, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugo","family":"Madeira","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Section of Rheumatology, Sta. Maria University Hospital, Lisbon, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo","family":"Macieira-Coelho","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Section of Rheumatology, Sta. 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