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Therefore some patients seem to be at risk, eg, patients with unstable diabetes type 1, sportsmen performing isometric exercise, and heavy smokers. In orthostatic hypotension, noncardioselective beta-blockers may be beneficial. Cardiac output tends, however, to decrease, and patients with orthostatic hypotension will probably not benefit from this effect.<\/jats:p>","DOI":"10.1177\/000331978803900706","type":"journal-article","created":{"date-parts":[[2007,11,26]],"date-time":"2007-11-26T17:46:29Z","timestamp":1196099189000},"page":"587-596","source":"Crossref","is-referenced-by-count":16,"title":["Pressor Responses from Noncardioselective Beta-Blockers"],"prefix":"10.1177","volume":"39","author":[{"given":"Ton J. M.","family":"Cleophas","sequence":"first","affiliation":[{"name":"Department of Medicine, Merwede Hospital Sliedrecht Dordrecht, Sliedrecht, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frans H. 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