{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T18:14:41Z","timestamp":1777400081165,"version":"3.51.4"},"reference-count":8,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[1989,6,1]],"date-time":"1989-06-01T00:00:00Z","timestamp":612662400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Angiology"],"published-print":{"date-parts":[[1989,6]]},"abstract":"<jats:p>The authors studied the efficacy of intravenous (IV) (1.5-2 mg\/kg) and oral propafenone (450 to 900 mg\/day) in 16 patients with paroxysmal, sus tained, recurrent supraventricular tachycardia (SVT). In 5 patients IV propafenone was not given, because of intolerant SVT. Nine patients had Wolff-Parkinson-White syndrome.<\/jats:p>\n                  <jats:p>IV propafenone immediately stopped and prevented reinduction of SVT in 9\/11 patients. Oral propa fenone prevented SVT induction in 3 of 5 patients. In the 9 patients re sponsive to IV propafenone, oral pro pafenone was effective: in particular, in 6 patients SVT tachycardia was not induced by serial transesophageal pacings, and in the remaining 3 pa tients the arrhythmia was still in duced but was slower and of brief duration (3-5 seconds). In 11\/12 pa tients responsive to oral propafenone the minimum effective dosage in pre venting the induction of the arrhyth mia was 600 mg\/day. In only 1 patient was the dose of 450 mg\/day equally effective.<\/jats:p>\n                  <jats:p>Propafenone administration was not associated with major side ef fects. In conclusion, propafenone is very effective in the control of parox ysmal supraventricular tachycardia; intravenous propafenone can predict the efficacy of oral therapy.<\/jats:p>","DOI":"10.1177\/000331978904000608","type":"journal-article","created":{"date-parts":[[2008,7,28]],"date-time":"2008-07-28T17:57:07Z","timestamp":1217267827000},"page":"563-568","source":"Crossref","is-referenced-by-count":3,"title":["Paroxysmal Supraventricular Tachycardia: Experience with Propafenone"],"prefix":"10.1177","volume":"40","author":[{"given":"Vincenzo","family":"Santinelli","sequence":"first","affiliation":[{"name":"Department of Cardiology and Cardiac Surgery, University of Naples, Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario","family":"De Paola","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Cardiac Surgery, University of Naples, Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pietro","family":"Turco","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Cardiac Surgery, University of Naples, Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Domenico","family":"Smimmo","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Cardiac Surgery, University of Naples, Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Massimo","family":"Chiariello","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Cardiac Surgery, University of Naples, Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1989,6,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.eurheartj.a061621"},{"key":"atypb2","first-page":"461","volume":"228","author":"McLeon AA","year":"1984","journal-title":"J Pharmacol Exp Ther"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(87)80478-3"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(87)80479-5"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(84)80283-0"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(98)90076-6"},{"key":"atypb7","volume-title":"Management of supraventricular tachycardia with drugs and artificial pacing","author":"Krikler D.","year":"1979"},{"key":"atypb8","volume-title":"Role of pacing in treatment of supraventricular tachycardia","author":"Levy S.","year":"1984"}],"container-title":["Angiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000331978904000608","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000331978904000608","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T10:16:50Z","timestamp":1777371410000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/000331978904000608"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1989,6]]},"references-count":8,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1989,6]]}},"alternative-id":["10.1177\/000331978904000608"],"URL":"https:\/\/doi.org\/10.1177\/000331978904000608","relation":{},"ISSN":["0003-3197","1940-1574"],"issn-type":[{"value":"0003-3197","type":"print"},{"value":"1940-1574","type":"electronic"}],"subject":[],"published":{"date-parts":[[1989,6]]}}}