{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T17:57:37Z","timestamp":1777399057588,"version":"3.51.4"},"reference-count":18,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[1991,6,1]],"date-time":"1991-06-01T00:00:00Z","timestamp":675734400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Angiology"],"published-print":{"date-parts":[[1991,6]]},"abstract":"<jats:p>Two-dimensional echographic and color Doppler studies of the heart and carotid arteries (CA) were performed in 45 patients &gt; sixty-five years old without aortic stenosis, 23 with (Group 1) and 22 without (group 2) precordial ejection systolic murmur (SM). Aortic cusps thickening was found in 11 Group 1 (48%) and 2 Group 2 (9%) patients (p &lt; 0.001). Aortic root and aortic arch size were similar in the two groups. Maximum aortic flow velocity was significantly greater in Group 1 (200 60 cm\/sec) than in Group 2 (120 20 cm\/sec) (p &lt; 0.001). Left ventricular outflow systolic maximum velocity was similar in the two groups. A bilateral neck murmur was heard in 10\/23 Group 1 patients (43%); in this group, patients with cervical SM had a greater maximum aortic flow velocity than those without cervical SM (230 + 60 cm\/sec vs 172 + 32 cm\/sec, p &lt; 0.001). In Group 1, 3 patients had a cervical SM louder on one neck side; only in these 3 patients were ipsilateral obstructive CA plaques found. A unilateral neck SM was heard in 4\/22 Group 2 patients (18%); in these 4, ipsilateral obstructive CA were found.<\/jats:p>\n                  <jats:p>Conclusions: (1) in the elderly, precordial ejection SM is related to mild increase in maximum aortic flow velocity and thickening of aortic cusps; (2) in patients with precordial SM radiated to both neck sides, maximum aortic flow velocity tends to be more markedly increased; (3) in patients with precordial SM, a cervical SM louder on one neck side should suggest coexistent ipsilateral CA stenosis.<\/jats:p>","DOI":"10.1177\/000331979104200604","type":"journal-article","created":{"date-parts":[[2007,11,26]],"date-time":"2007-11-26T17:46:29Z","timestamp":1196099189000},"page":"455-461","source":"Crossref","is-referenced-by-count":6,"title":["Systolic Ejection Murmurs in the Elderly: Aortic Valve and Carotid Arteries Echo-Doppler Findings"],"prefix":"10.1177","volume":"42","author":[{"given":"Carlo","family":"Vigna","sequence":"first","affiliation":[{"name":"Division of Cardiology and the Section of Angiology, Ospedale Casa Sollievo della Sofferenza, San Giovanni Rotondo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matteo","family":"Impagliatelli","sequence":"additional","affiliation":[{"name":"Division of Cardiology and the Section of Angiology, Ospedale Casa Sollievo della Sofferenza, San Giovanni Rotondo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aldo","family":"Russo","sequence":"additional","affiliation":[{"name":"Division of Cardiology and the Section of Angiology, Ospedale Casa Sollievo della Sofferenza, San Giovanni Rotondo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michele","family":"Pacilli","sequence":"additional","affiliation":[{"name":"Division of Cardiology and the Section of Angiology, Ospedale Casa Sollievo della Sofferenza, San Giovanni Rotondo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincenzo","family":"De Rito","sequence":"additional","affiliation":[{"name":"Division of Cardiology and the Section of Angiology, Ospedale Casa Sollievo della Sofferenza, San Giovanni Rotondo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gian Piero","family":"Perna","sequence":"additional","affiliation":[{"name":"Division of Cardiology and the Section of Angiology, Ospedale Casa Sollievo della Sofferenza, San Giovanni Rotondo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro","family":"Villella","sequence":"additional","affiliation":[{"name":"Division of Cardiology and the Section of Angiology, Ospedale Casa Sollievo della Sofferenza, San Giovanni Rotondo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tommaso","family":"Langialonga","sequence":"additional","affiliation":[{"name":"Division of Cardiology and the Section of Angiology, Ospedale Casa Sollievo della Sofferenza, San Giovanni Rotondo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raffaele","family":"Fanelli","sequence":"additional","affiliation":[{"name":"Division of Cardiology and the Section of Angiology, Ospedale Casa Sollievo della Sofferenza, San Giovanni Rotondo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriele","family":"Rinelli","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Catholic University \"Sacro Cuore\", Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonella","family":"Lombardo","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Catholic University \"Sacro Cuore\", Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Loperfido","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Catholic University \"Sacro Cuore\", Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1991,6,1]]},"reference":[{"key":"atypb1","unstructured":"Noble RJ, Rothbaum DA: Geriatric Cardiology. Philadelphia: FA Davis Company, 1981, pp 55-64."},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(83)90370-7"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.7863\/jum.1987.6.7.363"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1007\/978-94-009-4305-6_17"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(88)80019-6"},{"key":"atypb6","unstructured":"Craige E.: Echophonocardiography and othernininvasive techniques to elucidate heart murmurs . In: The Heart, ed. by Braunwald E. Philadelphia: WB Saunders Company, 1988, pp 66-67."},{"key":"atypb7","unstructured":"Feigenbaum H.: Echocardiography. Philadelphia: Lea & Febiger, 1986, pp 279-287."},{"key":"atypb8","unstructured":"Weyman AE: Cross-Sectional Echocardiography. Philadelphia: Lea & Febiger, 1982, p 504."},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(89)90597-4"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(87)80254-1"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.54.4.396"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.70.3.425"},{"key":"atypb13","unstructured":"Zwiebel WJ: Introduction to Vascular Ultrasonography. Orlando: Grune & Stratton, 1986, pp 171-216."},{"key":"atypb14","unstructured":"Gerlock AJ Jr , Giyanani VL, Krebs C.: Applications of Noninvasive Techniques. Philadelphia: WB Saunders Company, 1988, pp 21-22."},{"key":"atypb15","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(86)90295-X"},{"key":"atypb16","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(87)90262-1"},{"key":"atypb17","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.15.4.605"},{"key":"atypb18","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198610023151404"}],"container-title":["Angiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000331979104200604","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000331979104200604","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T10:14:19Z","timestamp":1777371259000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/000331979104200604"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,6]]},"references-count":18,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1991,6]]}},"alternative-id":["10.1177\/000331979104200604"],"URL":"https:\/\/doi.org\/10.1177\/000331979104200604","relation":{},"ISSN":["0003-3197","1940-1574"],"issn-type":[{"value":"0003-3197","type":"print"},{"value":"1940-1574","type":"electronic"}],"subject":[],"published":{"date-parts":[[1991,6]]}}}