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Subjects were at least age sixty, (mean age 71.1). Mean bihemispheric cerebral blood flow and cognitive test scores of control subjects were significantly higher than those of both demented groups at entry and remained so. After adjustment for initial CBF, course over time was similar for all groups. Group variability was similar for CBF but not for cognition. Both IVD and DAT patients were more variable than controls but similar to each other. Throughout, DAT patients showed greater cognitive impairments than IVD patients. Cognitive impairments stabilized among IVD patients treated by control of risk factors, antiplatelet or anticoagulant therapy but declined progressively among DAT patients.<\/jats:p>","DOI":"10.1177\/000331979404500301","type":"journal-article","created":{"date-parts":[[2008,7,28]],"date-time":"2008-07-28T17:57:07Z","timestamp":1217267827000},"page":"171-180","source":"Crossref","is-referenced-by-count":9,"title":["Prospective Studies of Cerebral Perfusion and Cognitive Testing Among Elderly Normal Volunteers and Patients with Ischemic Vascular Dementia and Alzheimer's Disease"],"prefix":"10.1177","volume":"45","author":[{"given":"Karl F.","family":"Mortel","sequence":"first","affiliation":[{"name":"Cerebral Blood Flow Laboratory, Veterans Affairs Medical Center; Department of Neurology, Baylor College of Medicine, Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marykay A.","family":"Pavol","sequence":"additional","affiliation":[{"name":"Cerebral Blood Flow Laboratory, Veterans Affairs Medical Center; Department of Neurology, Baylor College of Medicine, Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stacey","family":"Wood","sequence":"additional","affiliation":[{"name":"Cerebral Blood Flow Laboratory, Veterans Affairs Medical Center; Department of Neurology, Baylor College of Medicine, Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John S.","family":"Meyer","sequence":"additional","affiliation":[{"name":"Cerebral Blood Flow Laboratory, Veterans Affairs Medical Center; Department of Neurology, Baylor College of Medicine, Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuo","family":"Terayama","sequence":"additional","affiliation":[{"name":"Cerebral Blood Flow Laboratory, Veterans Affairs Medical Center; Department of Neurology, Baylor College of Medicine, Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennie L.","family":"Rexer","sequence":"additional","affiliation":[{"name":"Cerebral Blood Flow Laboratory, Veterans Affairs Medical Center; Department of Neurology, Baylor College of Medicine, Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian","family":"Herod","sequence":"additional","affiliation":[{"name":"Cerebral Blood Flow Laboratory, Veterans Affairs Medical Center; Department of Neurology, Baylor College of Medicine, Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1994,3,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1159\/000212833"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1987.01800170019003"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410300611"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.41.12.1886"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.42.1.115"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.51.12.1489"},{"key":"atypb7","unstructured":"Meyer J., Rogers R., Mortel K.: Multi-infarct dementia: Demography, risk factors, and therapy. 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